Sleep Dysfunction in COVID-19 Patients: Prevalence, Risk Factors, Mechanisms, and Management

During the COVID-19 pandemic, the need to establish the prevalence of sleep dysfunction and psychological distress, identify predisposing and protective factors, and explore effective management strategies remains an important priority. Evidence to date suggests that a considerable proportion of COV...

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Autores principales:	Athanasia Pataka, Seraphim Kotoulas, Elpitha Sakka, Paraskevi Katsaounou, Sofia Pappa
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	COVID-19 patients sleep dysfunction mental health insomnia obstructive sleep apnea Medicine R
Acceso en línea:	https://doaj.org/article/e29b91ac87914d3884468dd4ceab0fbe
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spelling	oai:doaj.org-article:e29b91ac87914d3884468dd4ceab0fbe2021-11-25T18:07:59ZSleep Dysfunction in COVID-19 Patients: Prevalence, Risk Factors, Mechanisms, and Management10.3390/jpm111112032075-4426https://doaj.org/article/e29b91ac87914d3884468dd4ceab0fbe2021-11-01T00:00:00Zhttps://www.mdpi.com/2075-4426/11/11/1203https://doaj.org/toc/2075-4426During the COVID-19 pandemic, the need to establish the prevalence of sleep dysfunction and psychological distress, identify predisposing and protective factors, and explore effective management strategies remains an important priority. Evidence to date suggests that a considerable proportion of COVID-19 patients experience significant sleep disturbances (estimated to afflict up to 50–75%) as well as psychological distress such as depression, anxiety, and traumatic stress. Duration of hospitalization, pre-existing mental health concerns, lower absolute lymphocyte count, and increased neutrophil-to-lymphocyte ratio have been all associated with a greater risk of sleep dysfunction in infected and hospitalized patients. Furthermore, in this review, we discuss the link between sleep deprivation, susceptibility to viral infections, and psychosocial wellbeing in relevance to COVID-19 and summarize the existing evidence regarding the presence and role of sleep apnea in infected individuals. Finally, we highlight the importance of suitable interventions in order to prevent and manage sleep dysfunction and avoid long-term physical and psychological implications. Future research should aim to provide high-quality information including in high risk, underserved, or difficult to reach populations and on the long-term consequences and effectiveness of applied interventions.Athanasia PatakaSeraphim KotoulasElpitha SakkaParaskevi KatsaounouSofia PappaMDPI AGarticleCOVID-19 patientssleep dysfunctionmental healthinsomniaobstructive sleep apneaMedicineRENJournal of Personalized Medicine, Vol 11, Iss 1203, p 1203 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	COVID-19 patients sleep dysfunction mental health insomnia obstructive sleep apnea Medicine R
spellingShingle	COVID-19 patients sleep dysfunction mental health insomnia obstructive sleep apnea Medicine R Athanasia Pataka Seraphim Kotoulas Elpitha Sakka Paraskevi Katsaounou Sofia Pappa Sleep Dysfunction in COVID-19 Patients: Prevalence, Risk Factors, Mechanisms, and Management
description	During the COVID-19 pandemic, the need to establish the prevalence of sleep dysfunction and psychological distress, identify predisposing and protective factors, and explore effective management strategies remains an important priority. Evidence to date suggests that a considerable proportion of COVID-19 patients experience significant sleep disturbances (estimated to afflict up to 50–75%) as well as psychological distress such as depression, anxiety, and traumatic stress. Duration of hospitalization, pre-existing mental health concerns, lower absolute lymphocyte count, and increased neutrophil-to-lymphocyte ratio have been all associated with a greater risk of sleep dysfunction in infected and hospitalized patients. Furthermore, in this review, we discuss the link between sleep deprivation, susceptibility to viral infections, and psychosocial wellbeing in relevance to COVID-19 and summarize the existing evidence regarding the presence and role of sleep apnea in infected individuals. Finally, we highlight the importance of suitable interventions in order to prevent and manage sleep dysfunction and avoid long-term physical and psychological implications. Future research should aim to provide high-quality information including in high risk, underserved, or difficult to reach populations and on the long-term consequences and effectiveness of applied interventions.
format	article
author	Athanasia Pataka Seraphim Kotoulas Elpitha Sakka Paraskevi Katsaounou Sofia Pappa
author_facet	Athanasia Pataka Seraphim Kotoulas Elpitha Sakka Paraskevi Katsaounou Sofia Pappa
author_sort	Athanasia Pataka
title	Sleep Dysfunction in COVID-19 Patients: Prevalence, Risk Factors, Mechanisms, and Management
title_short	Sleep Dysfunction in COVID-19 Patients: Prevalence, Risk Factors, Mechanisms, and Management
title_full	Sleep Dysfunction in COVID-19 Patients: Prevalence, Risk Factors, Mechanisms, and Management
title_fullStr	Sleep Dysfunction in COVID-19 Patients: Prevalence, Risk Factors, Mechanisms, and Management
title_full_unstemmed	Sleep Dysfunction in COVID-19 Patients: Prevalence, Risk Factors, Mechanisms, and Management
title_sort	sleep dysfunction in covid-19 patients: prevalence, risk factors, mechanisms, and management
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/e29b91ac87914d3884468dd4ceab0fbe
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Sleep Dysfunction in COVID-19 Patients: Prevalence, Risk Factors, Mechanisms, and Management

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