High capacity in G protein-coupled receptor signaling

G protein-coupled receptors (GPCRs) activate intracellular signalling pathways upon extracellular stimulation. Here authors record single cell responses of GPCR signalling which allows the direct estimation of its channel capacity for each cell along with the reproducibility of its response.

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Autores principales: Amiran Keshelava, Gonzalo P. Solis, Micha Hersch, Alexey Koval, Mikhail Kryuchkov, Sven Bergmann, Vladimir L. Katanaev
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/e2b10c70e16e40f196b3c188a5647db1
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spelling oai:doaj.org-article:e2b10c70e16e40f196b3c188a5647db12021-12-02T17:31:46ZHigh capacity in G protein-coupled receptor signaling10.1038/s41467-018-02868-y2041-1723https://doaj.org/article/e2b10c70e16e40f196b3c188a5647db12018-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-02868-yhttps://doaj.org/toc/2041-1723G protein-coupled receptors (GPCRs) activate intracellular signalling pathways upon extracellular stimulation. Here authors record single cell responses of GPCR signalling which allows the direct estimation of its channel capacity for each cell along with the reproducibility of its response.Amiran KeshelavaGonzalo P. SolisMicha HerschAlexey KovalMikhail KryuchkovSven BergmannVladimir L. KatanaevNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-8 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Amiran Keshelava
Gonzalo P. Solis
Micha Hersch
Alexey Koval
Mikhail Kryuchkov
Sven Bergmann
Vladimir L. Katanaev
High capacity in G protein-coupled receptor signaling
description G protein-coupled receptors (GPCRs) activate intracellular signalling pathways upon extracellular stimulation. Here authors record single cell responses of GPCR signalling which allows the direct estimation of its channel capacity for each cell along with the reproducibility of its response.
format article
author Amiran Keshelava
Gonzalo P. Solis
Micha Hersch
Alexey Koval
Mikhail Kryuchkov
Sven Bergmann
Vladimir L. Katanaev
author_facet Amiran Keshelava
Gonzalo P. Solis
Micha Hersch
Alexey Koval
Mikhail Kryuchkov
Sven Bergmann
Vladimir L. Katanaev
author_sort Amiran Keshelava
title High capacity in G protein-coupled receptor signaling
title_short High capacity in G protein-coupled receptor signaling
title_full High capacity in G protein-coupled receptor signaling
title_fullStr High capacity in G protein-coupled receptor signaling
title_full_unstemmed High capacity in G protein-coupled receptor signaling
title_sort high capacity in g protein-coupled receptor signaling
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/e2b10c70e16e40f196b3c188a5647db1
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AT gonzalopsolis highcapacityingproteincoupledreceptorsignaling
AT michahersch highcapacityingproteincoupledreceptorsignaling
AT alexeykoval highcapacityingproteincoupledreceptorsignaling
AT mikhailkryuchkov highcapacityingproteincoupledreceptorsignaling
AT svenbergmann highcapacityingproteincoupledreceptorsignaling
AT vladimirlkatanaev highcapacityingproteincoupledreceptorsignaling
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