High capacity in G protein-coupled receptor signaling
G protein-coupled receptors (GPCRs) activate intracellular signalling pathways upon extracellular stimulation. Here authors record single cell responses of GPCR signalling which allows the direct estimation of its channel capacity for each cell along with the reproducibility of its response.
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Nature Portfolio
2018
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oai:doaj.org-article:e2b10c70e16e40f196b3c188a5647db12021-12-02T17:31:46ZHigh capacity in G protein-coupled receptor signaling10.1038/s41467-018-02868-y2041-1723https://doaj.org/article/e2b10c70e16e40f196b3c188a5647db12018-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-02868-yhttps://doaj.org/toc/2041-1723G protein-coupled receptors (GPCRs) activate intracellular signalling pathways upon extracellular stimulation. Here authors record single cell responses of GPCR signalling which allows the direct estimation of its channel capacity for each cell along with the reproducibility of its response.Amiran KeshelavaGonzalo P. SolisMicha HerschAlexey KovalMikhail KryuchkovSven BergmannVladimir L. KatanaevNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-8 (2018) |
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Science Q Amiran Keshelava Gonzalo P. Solis Micha Hersch Alexey Koval Mikhail Kryuchkov Sven Bergmann Vladimir L. Katanaev High capacity in G protein-coupled receptor signaling |
description |
G protein-coupled receptors (GPCRs) activate intracellular signalling pathways upon extracellular stimulation. Here authors record single cell responses of GPCR signalling which allows the direct estimation of its channel capacity for each cell along with the reproducibility of its response. |
format |
article |
author |
Amiran Keshelava Gonzalo P. Solis Micha Hersch Alexey Koval Mikhail Kryuchkov Sven Bergmann Vladimir L. Katanaev |
author_facet |
Amiran Keshelava Gonzalo P. Solis Micha Hersch Alexey Koval Mikhail Kryuchkov Sven Bergmann Vladimir L. Katanaev |
author_sort |
Amiran Keshelava |
title |
High capacity in G protein-coupled receptor signaling |
title_short |
High capacity in G protein-coupled receptor signaling |
title_full |
High capacity in G protein-coupled receptor signaling |
title_fullStr |
High capacity in G protein-coupled receptor signaling |
title_full_unstemmed |
High capacity in G protein-coupled receptor signaling |
title_sort |
high capacity in g protein-coupled receptor signaling |
publisher |
Nature Portfolio |
publishDate |
2018 |
url |
https://doaj.org/article/e2b10c70e16e40f196b3c188a5647db1 |
work_keys_str_mv |
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_version_ |
1718380526293745664 |