Role of the Stria Vascularis in the Pathogenesis of Sensorineural Hearing Loss: A Narrative Review

Sensorineural hearing loss is a common sensory impairment in humans caused by abnormalities in the inner ear. The stria vascularis is regarded as a major cochlear structure that can independently degenerate and influence the degree of hearing loss. This review summarizes the current literature on th...

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Autores principales:	Wenting Yu, Shimin Zong, Peiyu Du, Peng Zhou, Hejie Li, Enhao Wang, Hongjun Xiao
Formato:	article
Lenguaje:	EN
Publicado:	Frontiers Media S.A. 2021
Materias:	sensorineural hearing loss stria vascularis pathogenesis cell signaling molecular factors Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571
Acceso en línea:	https://doaj.org/article/e2b1f38d0d044fabb9eaab3d2823c0a0
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spelling	oai:doaj.org-article:e2b1f38d0d044fabb9eaab3d2823c0a02021-11-19T05:44:42ZRole of the Stria Vascularis in the Pathogenesis of Sensorineural Hearing Loss: A Narrative Review1662-453X10.3389/fnins.2021.774585https://doaj.org/article/e2b1f38d0d044fabb9eaab3d2823c0a02021-11-01T00:00:00Zhttps://www.frontiersin.org/articles/10.3389/fnins.2021.774585/fullhttps://doaj.org/toc/1662-453XSensorineural hearing loss is a common sensory impairment in humans caused by abnormalities in the inner ear. The stria vascularis is regarded as a major cochlear structure that can independently degenerate and influence the degree of hearing loss. This review summarizes the current literature on the role of the stria vascularis in the pathogenesis of sensorineural hearing loss resulting from different etiologies, focusing on both molecular events and signaling pathways, and further attempts to explore the underlying mechanisms at the cellular and molecular biological levels. In addition, the deficiencies and limitations of this field are discussed. With the rapid progress in scientific technology, new opportunities are arising to fully understand the role of the stria vascularis in the pathogenesis of sensorineural hearing loss, which, in the future, will hopefully lead to the prevention, early diagnosis, and improved treatment of sensorineural hearing loss.Wenting YuShimin ZongPeiyu DuPeng ZhouHejie LiEnhao WangHongjun XiaoFrontiers Media S.A.articlesensorineural hearing lossstria vascularispathogenesiscell signalingmolecular factorsNeurosciences. Biological psychiatry. NeuropsychiatryRC321-571ENFrontiers in Neuroscience, Vol 15 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	sensorineural hearing loss stria vascularis pathogenesis cell signaling molecular factors Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571
spellingShingle	sensorineural hearing loss stria vascularis pathogenesis cell signaling molecular factors Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Wenting Yu Shimin Zong Peiyu Du Peng Zhou Hejie Li Enhao Wang Hongjun Xiao Role of the Stria Vascularis in the Pathogenesis of Sensorineural Hearing Loss: A Narrative Review
description	Sensorineural hearing loss is a common sensory impairment in humans caused by abnormalities in the inner ear. The stria vascularis is regarded as a major cochlear structure that can independently degenerate and influence the degree of hearing loss. This review summarizes the current literature on the role of the stria vascularis in the pathogenesis of sensorineural hearing loss resulting from different etiologies, focusing on both molecular events and signaling pathways, and further attempts to explore the underlying mechanisms at the cellular and molecular biological levels. In addition, the deficiencies and limitations of this field are discussed. With the rapid progress in scientific technology, new opportunities are arising to fully understand the role of the stria vascularis in the pathogenesis of sensorineural hearing loss, which, in the future, will hopefully lead to the prevention, early diagnosis, and improved treatment of sensorineural hearing loss.
format	article
author	Wenting Yu Shimin Zong Peiyu Du Peng Zhou Hejie Li Enhao Wang Hongjun Xiao
author_facet	Wenting Yu Shimin Zong Peiyu Du Peng Zhou Hejie Li Enhao Wang Hongjun Xiao
author_sort	Wenting Yu
title	Role of the Stria Vascularis in the Pathogenesis of Sensorineural Hearing Loss: A Narrative Review
title_short	Role of the Stria Vascularis in the Pathogenesis of Sensorineural Hearing Loss: A Narrative Review
title_full	Role of the Stria Vascularis in the Pathogenesis of Sensorineural Hearing Loss: A Narrative Review
title_fullStr	Role of the Stria Vascularis in the Pathogenesis of Sensorineural Hearing Loss: A Narrative Review
title_full_unstemmed	Role of the Stria Vascularis in the Pathogenesis of Sensorineural Hearing Loss: A Narrative Review
title_sort	role of the stria vascularis in the pathogenesis of sensorineural hearing loss: a narrative review
publisher	Frontiers Media S.A.
publishDate	2021
url	https://doaj.org/article/e2b1f38d0d044fabb9eaab3d2823c0a0
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_version_	1718420406330720256

Role of the Stria Vascularis in the Pathogenesis of Sensorineural Hearing Loss: A Narrative Review

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