CRISPR/Cas9-Mediated Gene Disruption Reveals the Importance of Zinc Metabolism for Fitness of the Dimorphic Fungal Pathogen <named-content content-type="genus-species">Blastomyces dermatitidis</named-content>

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CRISPR/Cas9-Mediated Gene Disruption Reveals the Importance of Zinc Metabolism for Fitness of the Dimorphic Fungal Pathogen <named-content content-type="genus-species">Blastomyces dermatitidis</named-content>

ABSTRACT Blastomyces dermatitidis is a human fungal pathogen of the lung that can lead to disseminated disease in healthy and immunocompromised individuals. Genetic analysis of this fungus is hampered by the relative inefficiency of traditional recombination-based gene-targeting approaches. Here, we...

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Autores principales:	Gregory C. Kujoth, Thomas D. Sullivan, Richard Merkhofer, Taek-Jin Lee, Huafeng Wang, Tristan Brandhorst, Marcel Wüthrich, Bruce S. Klein
Formato:	article
Lenguaje:	EN
Publicado:	American Society for Microbiology 2018
Materias:	CRISPR fungi genetics pathogenesis virulence Microbiology QR1-502
Acceso en línea:	https://doaj.org/article/e2b61624f02c4953831471247fdb9457
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

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