NMDA-receptor-dependent plasticity in the bed nucleus of the stria terminalis triggers long-term anxiolysis

The bed nucleus of the stria terminalis (BNST) is known to modulate anxiety-related behaviours. Here the authors show that excitatory inputs from infralimbic cortex and ventral subiculum/CA1 converge onto the same BNST neurons; stimulation of vSUB/CA1 triggers LTP in BNST and reduces anxiety in rats...

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Autores principales: Christelle Glangetas, Léma Massi, Giulia R. Fois, Marion Jalabert, Delphine Girard, Marco Diana, Keisuke Yonehara, Botond Roska, Chun Xu, Andreas Lüthi, Stéphanie Caille, François Georges
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Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/e2b7ca07f8d94f6cbd85ff0e36985abd
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spelling oai:doaj.org-article:e2b7ca07f8d94f6cbd85ff0e36985abd2021-12-02T14:42:26ZNMDA-receptor-dependent plasticity in the bed nucleus of the stria terminalis triggers long-term anxiolysis10.1038/ncomms144562041-1723https://doaj.org/article/e2b7ca07f8d94f6cbd85ff0e36985abd2017-02-01T00:00:00Zhttps://doi.org/10.1038/ncomms14456https://doaj.org/toc/2041-1723The bed nucleus of the stria terminalis (BNST) is known to modulate anxiety-related behaviours. Here the authors show that excitatory inputs from infralimbic cortex and ventral subiculum/CA1 converge onto the same BNST neurons; stimulation of vSUB/CA1 triggers LTP in BNST and reduces anxiety in rats.Christelle GlangetasLéma MassiGiulia R. FoisMarion JalabertDelphine GirardMarco DianaKeisuke YoneharaBotond RoskaChun XuAndreas LüthiStéphanie CailleFrançois GeorgesNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-7 (2017)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Christelle Glangetas
Léma Massi
Giulia R. Fois
Marion Jalabert
Delphine Girard
Marco Diana
Keisuke Yonehara
Botond Roska
Chun Xu
Andreas Lüthi
Stéphanie Caille
François Georges
NMDA-receptor-dependent plasticity in the bed nucleus of the stria terminalis triggers long-term anxiolysis
description The bed nucleus of the stria terminalis (BNST) is known to modulate anxiety-related behaviours. Here the authors show that excitatory inputs from infralimbic cortex and ventral subiculum/CA1 converge onto the same BNST neurons; stimulation of vSUB/CA1 triggers LTP in BNST and reduces anxiety in rats.
format article
author Christelle Glangetas
Léma Massi
Giulia R. Fois
Marion Jalabert
Delphine Girard
Marco Diana
Keisuke Yonehara
Botond Roska
Chun Xu
Andreas Lüthi
Stéphanie Caille
François Georges
author_facet Christelle Glangetas
Léma Massi
Giulia R. Fois
Marion Jalabert
Delphine Girard
Marco Diana
Keisuke Yonehara
Botond Roska
Chun Xu
Andreas Lüthi
Stéphanie Caille
François Georges
author_sort Christelle Glangetas
title NMDA-receptor-dependent plasticity in the bed nucleus of the stria terminalis triggers long-term anxiolysis
title_short NMDA-receptor-dependent plasticity in the bed nucleus of the stria terminalis triggers long-term anxiolysis
title_full NMDA-receptor-dependent plasticity in the bed nucleus of the stria terminalis triggers long-term anxiolysis
title_fullStr NMDA-receptor-dependent plasticity in the bed nucleus of the stria terminalis triggers long-term anxiolysis
title_full_unstemmed NMDA-receptor-dependent plasticity in the bed nucleus of the stria terminalis triggers long-term anxiolysis
title_sort nmda-receptor-dependent plasticity in the bed nucleus of the stria terminalis triggers long-term anxiolysis
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/e2b7ca07f8d94f6cbd85ff0e36985abd
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