NMDA-receptor-dependent plasticity in the bed nucleus of the stria terminalis triggers long-term anxiolysis
The bed nucleus of the stria terminalis (BNST) is known to modulate anxiety-related behaviours. Here the authors show that excitatory inputs from infralimbic cortex and ventral subiculum/CA1 converge onto the same BNST neurons; stimulation of vSUB/CA1 triggers LTP in BNST and reduces anxiety in rats...
Guardado en:
| Autores principales: | , , , , , , , , , , , |
|---|---|
| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
Nature Portfolio
2017
|
| Materias: | |
| Acceso en línea: | https://doaj.org/article/e2b7ca07f8d94f6cbd85ff0e36985abd |
| Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
| id |
oai:doaj.org-article:e2b7ca07f8d94f6cbd85ff0e36985abd |
|---|---|
| record_format |
dspace |
| spelling |
oai:doaj.org-article:e2b7ca07f8d94f6cbd85ff0e36985abd2021-12-02T14:42:26ZNMDA-receptor-dependent plasticity in the bed nucleus of the stria terminalis triggers long-term anxiolysis10.1038/ncomms144562041-1723https://doaj.org/article/e2b7ca07f8d94f6cbd85ff0e36985abd2017-02-01T00:00:00Zhttps://doi.org/10.1038/ncomms14456https://doaj.org/toc/2041-1723The bed nucleus of the stria terminalis (BNST) is known to modulate anxiety-related behaviours. Here the authors show that excitatory inputs from infralimbic cortex and ventral subiculum/CA1 converge onto the same BNST neurons; stimulation of vSUB/CA1 triggers LTP in BNST and reduces anxiety in rats.Christelle GlangetasLéma MassiGiulia R. FoisMarion JalabertDelphine GirardMarco DianaKeisuke YoneharaBotond RoskaChun XuAndreas LüthiStéphanie CailleFrançois GeorgesNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-7 (2017) |
| institution |
DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
Science Q |
| spellingShingle |
Science Q Christelle Glangetas Léma Massi Giulia R. Fois Marion Jalabert Delphine Girard Marco Diana Keisuke Yonehara Botond Roska Chun Xu Andreas Lüthi Stéphanie Caille François Georges NMDA-receptor-dependent plasticity in the bed nucleus of the stria terminalis triggers long-term anxiolysis |
| description |
The bed nucleus of the stria terminalis (BNST) is known to modulate anxiety-related behaviours. Here the authors show that excitatory inputs from infralimbic cortex and ventral subiculum/CA1 converge onto the same BNST neurons; stimulation of vSUB/CA1 triggers LTP in BNST and reduces anxiety in rats. |
| format |
article |
| author |
Christelle Glangetas Léma Massi Giulia R. Fois Marion Jalabert Delphine Girard Marco Diana Keisuke Yonehara Botond Roska Chun Xu Andreas Lüthi Stéphanie Caille François Georges |
| author_facet |
Christelle Glangetas Léma Massi Giulia R. Fois Marion Jalabert Delphine Girard Marco Diana Keisuke Yonehara Botond Roska Chun Xu Andreas Lüthi Stéphanie Caille François Georges |
| author_sort |
Christelle Glangetas |
| title |
NMDA-receptor-dependent plasticity in the bed nucleus of the stria terminalis triggers long-term anxiolysis |
| title_short |
NMDA-receptor-dependent plasticity in the bed nucleus of the stria terminalis triggers long-term anxiolysis |
| title_full |
NMDA-receptor-dependent plasticity in the bed nucleus of the stria terminalis triggers long-term anxiolysis |
| title_fullStr |
NMDA-receptor-dependent plasticity in the bed nucleus of the stria terminalis triggers long-term anxiolysis |
| title_full_unstemmed |
NMDA-receptor-dependent plasticity in the bed nucleus of the stria terminalis triggers long-term anxiolysis |
| title_sort |
nmda-receptor-dependent plasticity in the bed nucleus of the stria terminalis triggers long-term anxiolysis |
| publisher |
Nature Portfolio |
| publishDate |
2017 |
| url |
https://doaj.org/article/e2b7ca07f8d94f6cbd85ff0e36985abd |
| work_keys_str_mv |
AT christelleglangetas nmdareceptordependentplasticityinthebednucleusofthestriaterminalistriggerslongtermanxiolysis AT lemamassi nmdareceptordependentplasticityinthebednucleusofthestriaterminalistriggerslongtermanxiolysis AT giuliarfois nmdareceptordependentplasticityinthebednucleusofthestriaterminalistriggerslongtermanxiolysis AT marionjalabert nmdareceptordependentplasticityinthebednucleusofthestriaterminalistriggerslongtermanxiolysis AT delphinegirard nmdareceptordependentplasticityinthebednucleusofthestriaterminalistriggerslongtermanxiolysis AT marcodiana nmdareceptordependentplasticityinthebednucleusofthestriaterminalistriggerslongtermanxiolysis AT keisukeyonehara nmdareceptordependentplasticityinthebednucleusofthestriaterminalistriggerslongtermanxiolysis AT botondroska nmdareceptordependentplasticityinthebednucleusofthestriaterminalistriggerslongtermanxiolysis AT chunxu nmdareceptordependentplasticityinthebednucleusofthestriaterminalistriggerslongtermanxiolysis AT andreasluthi nmdareceptordependentplasticityinthebednucleusofthestriaterminalistriggerslongtermanxiolysis AT stephaniecaille nmdareceptordependentplasticityinthebednucleusofthestriaterminalistriggerslongtermanxiolysis AT francoisgeorges nmdareceptordependentplasticityinthebednucleusofthestriaterminalistriggerslongtermanxiolysis |
| _version_ |
1718389722009567232 |