NMDA-receptor-dependent plasticity in the bed nucleus of the stria terminalis triggers long-term anxiolysis
The bed nucleus of the stria terminalis (BNST) is known to modulate anxiety-related behaviours. Here the authors show that excitatory inputs from infralimbic cortex and ventral subiculum/CA1 converge onto the same BNST neurons; stimulation of vSUB/CA1 triggers LTP in BNST and reduces anxiety in rats...
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Nature Portfolio
2017
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oai:doaj.org-article:e2b7ca07f8d94f6cbd85ff0e36985abd2021-12-02T14:42:26ZNMDA-receptor-dependent plasticity in the bed nucleus of the stria terminalis triggers long-term anxiolysis10.1038/ncomms144562041-1723https://doaj.org/article/e2b7ca07f8d94f6cbd85ff0e36985abd2017-02-01T00:00:00Zhttps://doi.org/10.1038/ncomms14456https://doaj.org/toc/2041-1723The bed nucleus of the stria terminalis (BNST) is known to modulate anxiety-related behaviours. Here the authors show that excitatory inputs from infralimbic cortex and ventral subiculum/CA1 converge onto the same BNST neurons; stimulation of vSUB/CA1 triggers LTP in BNST and reduces anxiety in rats.Christelle GlangetasLéma MassiGiulia R. FoisMarion JalabertDelphine GirardMarco DianaKeisuke YoneharaBotond RoskaChun XuAndreas LüthiStéphanie CailleFrançois GeorgesNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-7 (2017) |
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Science Q Christelle Glangetas Léma Massi Giulia R. Fois Marion Jalabert Delphine Girard Marco Diana Keisuke Yonehara Botond Roska Chun Xu Andreas Lüthi Stéphanie Caille François Georges NMDA-receptor-dependent plasticity in the bed nucleus of the stria terminalis triggers long-term anxiolysis |
description |
The bed nucleus of the stria terminalis (BNST) is known to modulate anxiety-related behaviours. Here the authors show that excitatory inputs from infralimbic cortex and ventral subiculum/CA1 converge onto the same BNST neurons; stimulation of vSUB/CA1 triggers LTP in BNST and reduces anxiety in rats. |
format |
article |
author |
Christelle Glangetas Léma Massi Giulia R. Fois Marion Jalabert Delphine Girard Marco Diana Keisuke Yonehara Botond Roska Chun Xu Andreas Lüthi Stéphanie Caille François Georges |
author_facet |
Christelle Glangetas Léma Massi Giulia R. Fois Marion Jalabert Delphine Girard Marco Diana Keisuke Yonehara Botond Roska Chun Xu Andreas Lüthi Stéphanie Caille François Georges |
author_sort |
Christelle Glangetas |
title |
NMDA-receptor-dependent plasticity in the bed nucleus of the stria terminalis triggers long-term anxiolysis |
title_short |
NMDA-receptor-dependent plasticity in the bed nucleus of the stria terminalis triggers long-term anxiolysis |
title_full |
NMDA-receptor-dependent plasticity in the bed nucleus of the stria terminalis triggers long-term anxiolysis |
title_fullStr |
NMDA-receptor-dependent plasticity in the bed nucleus of the stria terminalis triggers long-term anxiolysis |
title_full_unstemmed |
NMDA-receptor-dependent plasticity in the bed nucleus of the stria terminalis triggers long-term anxiolysis |
title_sort |
nmda-receptor-dependent plasticity in the bed nucleus of the stria terminalis triggers long-term anxiolysis |
publisher |
Nature Portfolio |
publishDate |
2017 |
url |
https://doaj.org/article/e2b7ca07f8d94f6cbd85ff0e36985abd |
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