Active intermixing of indirect and direct neurons builds the striatal mosaic
Striatal projection neurons exist as two distinct classes and are anatomically mixed in the brain. Here, Tinterri and colleagues show the developmental mechanism of this cellular mosaicism that relies on an intrinsic transcription factor for cell type specification and intermixed cellular migration.
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| Autores principales: | , , , , , , , , , , , , , , |
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| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
Nature Portfolio
2018
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| Materias: | |
| Acceso en línea: | https://doaj.org/article/e2b83ce586864e02bb8a6247f1fb68ff |
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| Sumario: | Striatal projection neurons exist as two distinct classes and are anatomically mixed in the brain. Here, Tinterri and colleagues show the developmental mechanism of this cellular mosaicism that relies on an intrinsic transcription factor for cell type specification and intermixed cellular migration. |
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