Active intermixing of indirect and direct neurons builds the striatal mosaic

Striatal projection neurons exist as two distinct classes and are anatomically mixed in the brain. Here, Tinterri and colleagues show the developmental mechanism of this cellular mosaicism that relies on an intrinsic transcription factor for cell type specification and intermixed cellular migration.

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Detalles Bibliográficos
Autores principales:	Andrea Tinterri, Fabien Menardy, Marco A. Diana, Ludmilla Lokmane, Maryama Keita, Fanny Coulpier, Sophie Lemoine, Caroline Mailhes, Benjamin Mathieu, Paloma Merchan-Sala, Kenneth Campbell, Ildiko Gyory, Rudolf Grosschedl, Daniela Popa, Sonia Garel
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/e2b83ce586864e02bb8a6247f1fb68ff
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spelling	oai:doaj.org-article:e2b83ce586864e02bb8a6247f1fb68ff2021-12-02T14:41:06ZActive intermixing of indirect and direct neurons builds the striatal mosaic10.1038/s41467-018-07171-42041-1723https://doaj.org/article/e2b83ce586864e02bb8a6247f1fb68ff2018-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-07171-4https://doaj.org/toc/2041-1723Striatal projection neurons exist as two distinct classes and are anatomically mixed in the brain. Here, Tinterri and colleagues show the developmental mechanism of this cellular mosaicism that relies on an intrinsic transcription factor for cell type specification and intermixed cellular migration.Andrea TinterriFabien MenardyMarco A. DianaLudmilla LokmaneMaryama KeitaFanny CoulpierSophie LemoineCaroline MailhesBenjamin MathieuPaloma Merchan-SalaKenneth CampbellIldiko GyoryRudolf GrosschedlDaniela PopaSonia GarelNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Andrea Tinterri Fabien Menardy Marco A. Diana Ludmilla Lokmane Maryama Keita Fanny Coulpier Sophie Lemoine Caroline Mailhes Benjamin Mathieu Paloma Merchan-Sala Kenneth Campbell Ildiko Gyory Rudolf Grosschedl Daniela Popa Sonia Garel Active intermixing of indirect and direct neurons builds the striatal mosaic
description	Striatal projection neurons exist as two distinct classes and are anatomically mixed in the brain. Here, Tinterri and colleagues show the developmental mechanism of this cellular mosaicism that relies on an intrinsic transcription factor for cell type specification and intermixed cellular migration.
format	article
author	Andrea Tinterri Fabien Menardy Marco A. Diana Ludmilla Lokmane Maryama Keita Fanny Coulpier Sophie Lemoine Caroline Mailhes Benjamin Mathieu Paloma Merchan-Sala Kenneth Campbell Ildiko Gyory Rudolf Grosschedl Daniela Popa Sonia Garel
author_facet	Andrea Tinterri Fabien Menardy Marco A. Diana Ludmilla Lokmane Maryama Keita Fanny Coulpier Sophie Lemoine Caroline Mailhes Benjamin Mathieu Paloma Merchan-Sala Kenneth Campbell Ildiko Gyory Rudolf Grosschedl Daniela Popa Sonia Garel
author_sort	Andrea Tinterri
title	Active intermixing of indirect and direct neurons builds the striatal mosaic
title_short	Active intermixing of indirect and direct neurons builds the striatal mosaic
title_full	Active intermixing of indirect and direct neurons builds the striatal mosaic
title_fullStr	Active intermixing of indirect and direct neurons builds the striatal mosaic
title_full_unstemmed	Active intermixing of indirect and direct neurons builds the striatal mosaic
title_sort	active intermixing of indirect and direct neurons builds the striatal mosaic
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/e2b83ce586864e02bb8a6247f1fb68ff
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Active intermixing of indirect and direct neurons builds the striatal mosaic

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