Long-acting injectable atovaquone nanomedicines for malaria prophylaxis

Long-acting antimalarials could provide improved prophylaxis and treatment options in the field. Here, Bakshi et al. develop a long-acting injectable atovaquone nanomedicine that prevents malaria infection prophylactically for up to 4 weeks in mice with no evidence for generation of resistant parasi...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Rahul P. Bakshi, Lee M. Tatham, Alison C. Savage, Abhai K. Tripathi, Godfree Mlambo, Matthew M. Ippolito, Elizabeth Nenortas, Steve P. Rannard, Andrew Owen, Theresa A. Shapiro
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/e2bbca833b9043c393d3ffbbdc23b805
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:e2bbca833b9043c393d3ffbbdc23b805
record_format	dspace
spelling	oai:doaj.org-article:e2bbca833b9043c393d3ffbbdc23b8052021-12-02T16:56:53ZLong-acting injectable atovaquone nanomedicines for malaria prophylaxis10.1038/s41467-017-02603-z2041-1723https://doaj.org/article/e2bbca833b9043c393d3ffbbdc23b8052018-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-02603-zhttps://doaj.org/toc/2041-1723Long-acting antimalarials could provide improved prophylaxis and treatment options in the field. Here, Bakshi et al. develop a long-acting injectable atovaquone nanomedicine that prevents malaria infection prophylactically for up to 4 weeks in mice with no evidence for generation of resistant parasites.Rahul P. BakshiLee M. TathamAlison C. SavageAbhai K. TripathiGodfree MlamboMatthew M. IppolitoElizabeth NenortasSteve P. RannardAndrew OwenTheresa A. ShapiroNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-8 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Rahul P. Bakshi Lee M. Tatham Alison C. Savage Abhai K. Tripathi Godfree Mlambo Matthew M. Ippolito Elizabeth Nenortas Steve P. Rannard Andrew Owen Theresa A. Shapiro Long-acting injectable atovaquone nanomedicines for malaria prophylaxis
description	Long-acting antimalarials could provide improved prophylaxis and treatment options in the field. Here, Bakshi et al. develop a long-acting injectable atovaquone nanomedicine that prevents malaria infection prophylactically for up to 4 weeks in mice with no evidence for generation of resistant parasites.
format	article
author	Rahul P. Bakshi Lee M. Tatham Alison C. Savage Abhai K. Tripathi Godfree Mlambo Matthew M. Ippolito Elizabeth Nenortas Steve P. Rannard Andrew Owen Theresa A. Shapiro
author_facet	Rahul P. Bakshi Lee M. Tatham Alison C. Savage Abhai K. Tripathi Godfree Mlambo Matthew M. Ippolito Elizabeth Nenortas Steve P. Rannard Andrew Owen Theresa A. Shapiro
author_sort	Rahul P. Bakshi
title	Long-acting injectable atovaquone nanomedicines for malaria prophylaxis
title_short	Long-acting injectable atovaquone nanomedicines for malaria prophylaxis
title_full	Long-acting injectable atovaquone nanomedicines for malaria prophylaxis
title_fullStr	Long-acting injectable atovaquone nanomedicines for malaria prophylaxis
title_full_unstemmed	Long-acting injectable atovaquone nanomedicines for malaria prophylaxis
title_sort	long-acting injectable atovaquone nanomedicines for malaria prophylaxis
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/e2bbca833b9043c393d3ffbbdc23b805
work_keys_str_mv	AT rahulpbakshi longactinginjectableatovaquonenanomedicinesformalariaprophylaxis AT leemtatham longactinginjectableatovaquonenanomedicinesformalariaprophylaxis AT alisoncsavage longactinginjectableatovaquonenanomedicinesformalariaprophylaxis AT abhaiktripathi longactinginjectableatovaquonenanomedicinesformalariaprophylaxis AT godfreemlambo longactinginjectableatovaquonenanomedicinesformalariaprophylaxis AT matthewmippolito longactinginjectableatovaquonenanomedicinesformalariaprophylaxis AT elizabethnenortas longactinginjectableatovaquonenanomedicinesformalariaprophylaxis AT steveprannard longactinginjectableatovaquonenanomedicinesformalariaprophylaxis AT andrewowen longactinginjectableatovaquonenanomedicinesformalariaprophylaxis AT theresaashapiro longactinginjectableatovaquonenanomedicinesformalariaprophylaxis
_version_	1718382711791419392

Long-acting injectable atovaquone nanomedicines for malaria prophylaxis

Ejemplares similares