Physician’ attitudes to growth hormone replacement therapy in adults following pituitary surgery: Results of an online survey

Objective: The aim of this study was to evaluate physician attitudes and practices in the management of adult growth hormone deficiency (GHD) following pituitary surgery. Materials and Methods: An online questionnaire survey was sent to a sample group of physicians. Results: A total of 131 responden...

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Autores principales:	Aishah Ekhzaimy, Salem A Beshyah, Khaled M Al-Dahmani, Mussa H AlMalki
Formato:	article
Lenguaje:	EN
Publicado:	Thieme Medical and Scientific Publishers Pvt. Ltd. 2020
Materias:	adult growth hormone deficiency growth hormone insulin-like growth factor-1 Medicine R
Acceso en línea:	https://doaj.org/article/e2cae1ae2a2240fb938d8302f938a702
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spelling	oai:doaj.org-article:e2cae1ae2a2240fb938d8302f938a7022021-12-02T18:42:19ZPhysician’ attitudes to growth hormone replacement therapy in adults following pituitary surgery: Results of an online survey2231-07702249-446410.4103/ajm.ajm_46_20https://doaj.org/article/e2cae1ae2a2240fb938d8302f938a7022020-10-01T00:00:00Zhttp://www.thieme-connect.de/DOI/DOI?10.4103/ajm.ajm_46_20https://doaj.org/toc/2231-0770https://doaj.org/toc/2249-4464Objective: The aim of this study was to evaluate physician attitudes and practices in the management of adult growth hormone deficiency (GHD) following pituitary surgery. Materials and Methods: An online questionnaire survey was sent to a sample group of physicians. Results: A total of 131 respondents provided usable responses. More than three quarters were senior physicians, with most practicing in tertiary care centers (73%). Four-fifths of the respondents see at least 1 to 5 patients with GHD following pituitary surgery per year. Seventy-four percent acknowledge the benefit in principle of growth hormone replacement therapy (GHRT) for patients with GHD after pituitary surgery. Most respondents (84%) would only consider GHRT for symptomatic patients. However, 16% stated that patients with GHD after pituitary surgery generally suffer from the side effects of GHRT. Forty-four percent said that the serum insulin-like growth factor-1 (IGF-1) level is the best screening test for assessing GHD after pituitary surgery but 57% of the respondents would use IGF-I levels, and 29% the insulin tolerance test (ITT), in patients with a documented deficiency in three pituitary axes. The main barriers to long-term GHRT use were that it requires injections (67%), and is costly with limited supply (61%). Other reasons not to use GHRT include an absence of GHD symptoms and apparent GHT ineffectiveness (44%), physician lack of familiarity with the medication (40%), and lack of adherence to available guidelines (38%). Conclusion: This survey addressed physician attitudes and practices in recognizing and treating GHD in adult’s post-pituitary surgery. Regional guidelines must be developed to help address/tackle these issues and assist physicians in understanding and treating this condition.Aishah EkhzaimySalem A BeshyahKhaled M Al-DahmaniMussa H AlMalkiThieme Medical and Scientific Publishers Pvt. Ltd.articleadult growth hormone deficiencygrowth hormoneinsulin-like growth factor-1MedicineRENAvicenna Journal of Medicine, Vol 10, Iss 04, Pp 215-222 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	adult growth hormone deficiency growth hormone insulin-like growth factor-1 Medicine R
spellingShingle	adult growth hormone deficiency growth hormone insulin-like growth factor-1 Medicine R Aishah Ekhzaimy Salem A Beshyah Khaled M Al-Dahmani Mussa H AlMalki Physician’ attitudes to growth hormone replacement therapy in adults following pituitary surgery: Results of an online survey
description	Objective: The aim of this study was to evaluate physician attitudes and practices in the management of adult growth hormone deficiency (GHD) following pituitary surgery. Materials and Methods: An online questionnaire survey was sent to a sample group of physicians. Results: A total of 131 respondents provided usable responses. More than three quarters were senior physicians, with most practicing in tertiary care centers (73%). Four-fifths of the respondents see at least 1 to 5 patients with GHD following pituitary surgery per year. Seventy-four percent acknowledge the benefit in principle of growth hormone replacement therapy (GHRT) for patients with GHD after pituitary surgery. Most respondents (84%) would only consider GHRT for symptomatic patients. However, 16% stated that patients with GHD after pituitary surgery generally suffer from the side effects of GHRT. Forty-four percent said that the serum insulin-like growth factor-1 (IGF-1) level is the best screening test for assessing GHD after pituitary surgery but 57% of the respondents would use IGF-I levels, and 29% the insulin tolerance test (ITT), in patients with a documented deficiency in three pituitary axes. The main barriers to long-term GHRT use were that it requires injections (67%), and is costly with limited supply (61%). Other reasons not to use GHRT include an absence of GHD symptoms and apparent GHT ineffectiveness (44%), physician lack of familiarity with the medication (40%), and lack of adherence to available guidelines (38%). Conclusion: This survey addressed physician attitudes and practices in recognizing and treating GHD in adult’s post-pituitary surgery. Regional guidelines must be developed to help address/tackle these issues and assist physicians in understanding and treating this condition.
format	article
author	Aishah Ekhzaimy Salem A Beshyah Khaled M Al-Dahmani Mussa H AlMalki
author_facet	Aishah Ekhzaimy Salem A Beshyah Khaled M Al-Dahmani Mussa H AlMalki
author_sort	Aishah Ekhzaimy
title	Physician’ attitudes to growth hormone replacement therapy in adults following pituitary surgery: Results of an online survey
title_short	Physician’ attitudes to growth hormone replacement therapy in adults following pituitary surgery: Results of an online survey
title_full	Physician’ attitudes to growth hormone replacement therapy in adults following pituitary surgery: Results of an online survey
title_fullStr	Physician’ attitudes to growth hormone replacement therapy in adults following pituitary surgery: Results of an online survey
title_full_unstemmed	Physician’ attitudes to growth hormone replacement therapy in adults following pituitary surgery: Results of an online survey
title_sort	physician’ attitudes to growth hormone replacement therapy in adults following pituitary surgery: results of an online survey
publisher	Thieme Medical and Scientific Publishers Pvt. Ltd.
publishDate	2020
url	https://doaj.org/article/e2cae1ae2a2240fb938d8302f938a702
work_keys_str_mv	AT aishahekhzaimy physicianattitudestogrowthhormonereplacementtherapyinadultsfollowingpituitarysurgeryresultsofanonlinesurvey AT salemabeshyah physicianattitudestogrowthhormonereplacementtherapyinadultsfollowingpituitarysurgeryresultsofanonlinesurvey AT khaledmaldahmani physicianattitudestogrowthhormonereplacementtherapyinadultsfollowingpituitarysurgeryresultsofanonlinesurvey AT mussahalmalki physicianattitudestogrowthhormonereplacementtherapyinadultsfollowingpituitarysurgeryresultsofanonlinesurvey
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Physician’ attitudes to growth hormone replacement therapy in adults following pituitary surgery: Results of an online survey

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