A synthetic nanobody targeting RBD protects hamsters from SARS-CoV-2 infection

A synthetic nanobody targeting RBD protects hamsters from SARS-CoV-2 infection

Here, the authors report the engineering, structural and biological characterization of synthetic nanobodies (sybodies) that display potent therapeutic activity against SARS-CoV-2 infection in animal models via targeting the virus receptor-binding domain.

Saved in:
Bibliographic Details
Main Authors: Tingting Li, Hongmin Cai, Hebang Yao, Bingjie Zhou, Ning Zhang, Martje Fentener van Vlissingen, Thijs Kuiken, Wenyu Han, Corine H. GeurtsvanKessel, Yuhuan Gong, Yapei Zhao, Quan Shen, Wenming Qin, Xiao-Xu Tian, Chao Peng, Yanling Lai, Yanxing Wang, Cedric A. J. Hutter, Shu-Ming Kuo, Juan Bao, Caixuan Liu, Yifan Wang, Audrey S. Richard, Hervé Raoul, Jiaming Lan, Markus A. Seeger, Yao Cong, Barry Rockx, Gary Wong, Yuhai Bi, Dimitri Lavillette, Dianfan Li
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
Science
Q
Online Access:https://doaj.org/article/e2d2ef9db7c042d5ae0d4a35e2484adb
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doaj.org/article/e2d2ef9db7c042d5ae0d4a35e2484adb

Similar Items