Tissue fluidity mediated by adherens junction dynamics promotes planar cell polarity-driven ommatidial rotation

Ommatidial rotation in the Drosophila eye is a regulated process and a Planar Cell Polarity (PCP) cell motility model. Here, the authors show that tissue fluidity via junctional remodeling, as regulated by the PCP effector kinase Nemo, is critical for this cell motility process.

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Autores principales: Nabila Founounou, Reza Farhadifar, Giovanna M. Collu, Ursula Weber, Michael J. Shelley, Marek Mlodzik
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/e2d76438c92f4084b28793c08567e39a
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Sumario:Ommatidial rotation in the Drosophila eye is a regulated process and a Planar Cell Polarity (PCP) cell motility model. Here, the authors show that tissue fluidity via junctional remodeling, as regulated by the PCP effector kinase Nemo, is critical for this cell motility process.