Synthetic Lethality Reveals Mechanisms of <named-content content-type="genus-species">Mycobacterium tuberculosis</named-content> Resistance to β-Lactams

Synthetic Lethality Reveals Mechanisms of <named-content content-type="genus-species">Mycobacterium tuberculosis</named-content> Resistance to β-Lactams

ABSTRACT Most β-lactam antibiotics are ineffective against Mycobacterium tuberculosis due to the microbe’s innate resistance. The emergence of multidrug-resistant (MDR) and extensively drug-resistant (XDR) strains has prompted interest to repurpose this class of drugs. To identify the genetic determ...

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Autores principales: Shichun Lun, David Miranda, Andre Kubler, Haidan Guo, Mariama C. Maiga, Kathryn Winglee, Shaaretha Pelly, William R. Bishai
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2014
Materias:
Microbiology
QR1-502
Acceso en línea:https://doaj.org/article/e2d9cd97723049a59e324f884a5cd039
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