Kdo Hydrolase Is Required for <named-content content-type="genus-species">Francisella tularensis</named-content> Virulence and Evasion of TLR2-Mediated Innate Immunity

Kdo Hydrolase Is Required for <named-content content-type="genus-species">Francisella tularensis</named-content> Virulence and Evasion of TLR2-Mediated Innate Immunity

ABSTRACT The highly virulent Francisella tularensis subsp. tularensis has been classified as a category A bioterrorism agent. A live vaccine strain (LVS) has been developed but remains unlicensed in the United States because of an incomplete understanding of its attenuation. Lipopolysaccharide (LPS)...

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Bibliographic Details
Main Authors: Nihal A. Okan, Sabina Chalabaev, Tae-Hyun Kim, Avner Fink, Robin A. Ross, Dennis L. Kasper
Format: article
Language:EN
Published: American Society for Microbiology 2013
Subjects:
Microbiology
QR1-502
Online Access:https://doaj.org/article/e2dbee38dec14692b0a7218af97817a5
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