New frontiers in suicide vulnerability: immune system and sex hormones
Suicide is one of the leading causes of death worldwide and men have a higher risk of attempting and completing suicide than women. Accumulating evidence leads to a possible key role of the immune system and sex hormones in psychiatric conditions associated with suicide vulnerability (e.g., major de...
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2021
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oai:doaj.org-article:e2dc1cceae8b41d6bf8af435a6b5dc372021-11-20T05:14:13ZNew frontiers in suicide vulnerability: immune system and sex hormones2666-354610.1016/j.bbih.2021.100384https://doaj.org/article/e2dc1cceae8b41d6bf8af435a6b5dc372021-12-01T00:00:00Zhttp://www.sciencedirect.com/science/article/pii/S2666354621001873https://doaj.org/toc/2666-3546Suicide is one of the leading causes of death worldwide and men have a higher risk of attempting and completing suicide than women. Accumulating evidence leads to a possible key role of the immune system and sex hormones in psychiatric conditions associated with suicide vulnerability (e.g., major depressive disorder). Moreover, the literature highlights a dysregulation of the immune system and altered sex hormone levels in suicidal patients. Sex hormones and the immune system may have a role in suicide risk and sex differences in suicide vulnerability. This brief review emphasises a research area focused on a possible interplay between the immune system and sex hormones that may help develop a better understanding of suicide vulnerability in the perspective of sex-specific therapeutic approaches.Giulia LombardoElsevierarticleSuicideImmune systemSex hormonesSex differencesNeurosciences. Biological psychiatry. NeuropsychiatryRC321-571ENBrain, Behavior, & Immunity - Health, Vol 18, Iss , Pp 100384- (2021) |
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DOAJ |
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Suicide Immune system Sex hormones Sex differences Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 |
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Suicide Immune system Sex hormones Sex differences Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Giulia Lombardo New frontiers in suicide vulnerability: immune system and sex hormones |
description |
Suicide is one of the leading causes of death worldwide and men have a higher risk of attempting and completing suicide than women. Accumulating evidence leads to a possible key role of the immune system and sex hormones in psychiatric conditions associated with suicide vulnerability (e.g., major depressive disorder). Moreover, the literature highlights a dysregulation of the immune system and altered sex hormone levels in suicidal patients. Sex hormones and the immune system may have a role in suicide risk and sex differences in suicide vulnerability. This brief review emphasises a research area focused on a possible interplay between the immune system and sex hormones that may help develop a better understanding of suicide vulnerability in the perspective of sex-specific therapeutic approaches. |
format |
article |
author |
Giulia Lombardo |
author_facet |
Giulia Lombardo |
author_sort |
Giulia Lombardo |
title |
New frontiers in suicide vulnerability: immune system and sex hormones |
title_short |
New frontiers in suicide vulnerability: immune system and sex hormones |
title_full |
New frontiers in suicide vulnerability: immune system and sex hormones |
title_fullStr |
New frontiers in suicide vulnerability: immune system and sex hormones |
title_full_unstemmed |
New frontiers in suicide vulnerability: immune system and sex hormones |
title_sort |
new frontiers in suicide vulnerability: immune system and sex hormones |
publisher |
Elsevier |
publishDate |
2021 |
url |
https://doaj.org/article/e2dc1cceae8b41d6bf8af435a6b5dc37 |
work_keys_str_mv |
AT giulialombardo newfrontiersinsuicidevulnerabilityimmunesystemandsexhormones |
_version_ |
1718419514515783680 |