New frontiers in suicide vulnerability: immune system and sex hormones

Suicide is one of the leading causes of death worldwide and men have a higher risk of attempting and completing suicide than women. Accumulating evidence leads to a possible key role of the immune system and sex hormones in psychiatric conditions associated with suicide vulnerability (e.g., major de...

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Autor principal: Giulia Lombardo
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Lenguaje:EN
Publicado: Elsevier 2021
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Acceso en línea:https://doaj.org/article/e2dc1cceae8b41d6bf8af435a6b5dc37
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spelling oai:doaj.org-article:e2dc1cceae8b41d6bf8af435a6b5dc372021-11-20T05:14:13ZNew frontiers in suicide vulnerability: immune system and sex hormones2666-354610.1016/j.bbih.2021.100384https://doaj.org/article/e2dc1cceae8b41d6bf8af435a6b5dc372021-12-01T00:00:00Zhttp://www.sciencedirect.com/science/article/pii/S2666354621001873https://doaj.org/toc/2666-3546Suicide is one of the leading causes of death worldwide and men have a higher risk of attempting and completing suicide than women. Accumulating evidence leads to a possible key role of the immune system and sex hormones in psychiatric conditions associated with suicide vulnerability (e.g., major depressive disorder). Moreover, the literature highlights a dysregulation of the immune system and altered sex hormone levels in suicidal patients. Sex hormones and the immune system may have a role in suicide risk and sex differences in suicide vulnerability. This brief review emphasises a research area focused on a possible interplay between the immune system and sex hormones that may help develop a better understanding of suicide vulnerability in the perspective of sex-specific therapeutic approaches.Giulia LombardoElsevierarticleSuicideImmune systemSex hormonesSex differencesNeurosciences. Biological psychiatry. NeuropsychiatryRC321-571ENBrain, Behavior, & Immunity - Health, Vol 18, Iss , Pp 100384- (2021)
institution DOAJ
collection DOAJ
language EN
topic Suicide
Immune system
Sex hormones
Sex differences
Neurosciences. Biological psychiatry. Neuropsychiatry
RC321-571
spellingShingle Suicide
Immune system
Sex hormones
Sex differences
Neurosciences. Biological psychiatry. Neuropsychiatry
RC321-571
Giulia Lombardo
New frontiers in suicide vulnerability: immune system and sex hormones
description Suicide is one of the leading causes of death worldwide and men have a higher risk of attempting and completing suicide than women. Accumulating evidence leads to a possible key role of the immune system and sex hormones in psychiatric conditions associated with suicide vulnerability (e.g., major depressive disorder). Moreover, the literature highlights a dysregulation of the immune system and altered sex hormone levels in suicidal patients. Sex hormones and the immune system may have a role in suicide risk and sex differences in suicide vulnerability. This brief review emphasises a research area focused on a possible interplay between the immune system and sex hormones that may help develop a better understanding of suicide vulnerability in the perspective of sex-specific therapeutic approaches.
format article
author Giulia Lombardo
author_facet Giulia Lombardo
author_sort Giulia Lombardo
title New frontiers in suicide vulnerability: immune system and sex hormones
title_short New frontiers in suicide vulnerability: immune system and sex hormones
title_full New frontiers in suicide vulnerability: immune system and sex hormones
title_fullStr New frontiers in suicide vulnerability: immune system and sex hormones
title_full_unstemmed New frontiers in suicide vulnerability: immune system and sex hormones
title_sort new frontiers in suicide vulnerability: immune system and sex hormones
publisher Elsevier
publishDate 2021
url https://doaj.org/article/e2dc1cceae8b41d6bf8af435a6b5dc37
work_keys_str_mv AT giulialombardo newfrontiersinsuicidevulnerabilityimmunesystemandsexhormones
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