Overcoming evolved resistance to population-suppressing homing-based gene drives

Abstract The recent development of a CRISPR-Cas9-based homing system for the suppression of Anopheles gambiae is encouraging; however, with current designs, the slow emergence of homing-resistant alleles is expected to result in suppressed populations rapidly rebounding, as homing-resistant alleles...

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Autores principales: John M. Marshall, Anna Buchman, Héctor M. Sánchez C., Omar S. Akbari
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/e2e393ef8d1346af8d9d36efd77d8122
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