Overcoming evolved resistance to population-suppressing homing-based gene drives
Abstract The recent development of a CRISPR-Cas9-based homing system for the suppression of Anopheles gambiae is encouraging; however, with current designs, the slow emergence of homing-resistant alleles is expected to result in suppressed populations rapidly rebounding, as homing-resistant alleles...
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Autores principales: | John M. Marshall, Anna Buchman, Héctor M. Sánchez C., Omar S. Akbari |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2017
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Materias: | |
Acceso en línea: | https://doaj.org/article/e2e393ef8d1346af8d9d36efd77d8122 |
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