Recruitment of upper-limb motoneurons with epidural electrical stimulation of the cervical spinal cord

Recruitment of upper-limb motoneurons with epidural electrical stimulation of the cervical spinal cord

The efficacy of epidural electrical stimulation (EES) to engage arm muscles and improve movement after spinal cord injury is still unclear. Here, the authors investigated how EES can recruit upper-limb motor neurons by combining computational modelling with experiments in non-human primates.

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Autores principales: Nathan Greiner, Beatrice Barra, Giuseppe Schiavone, Henri Lorach, Nicholas James, Sara Conti, Melanie Kaeser, Florian Fallegger, Simon Borgognon, Stéphanie Lacour, Jocelyne Bloch, Grégoire Courtine, Marco Capogrosso
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/e2e43608aa6e42f2bb776ad62e0048f1
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spelling oai:doaj.org-article:e2e43608aa6e42f2bb776ad62e0048f12021-12-02T10:49:14ZRecruitment of upper-limb motoneurons with epidural electrical stimulation of the cervical spinal cord10.1038/s41467-020-20703-12041-1723https://doaj.org/article/e2e43608aa6e42f2bb776ad62e0048f12021-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-20703-1https://doaj.org/toc/2041-1723The efficacy of epidural electrical stimulation (EES) to engage arm muscles and improve movement after spinal cord injury is still unclear. Here, the authors investigated how EES can recruit upper-limb motor neurons by combining computational modelling with experiments in non-human primates.Nathan GreinerBeatrice BarraGiuseppe SchiavoneHenri LorachNicholas JamesSara ContiMelanie KaeserFlorian FalleggerSimon BorgognonStéphanie LacourJocelyne BlochGrégoire CourtineMarco CapogrossoNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Nathan Greiner
Beatrice Barra
Giuseppe Schiavone
Henri Lorach
Nicholas James
Sara Conti
Melanie Kaeser
Florian Fallegger
Simon Borgognon
Stéphanie Lacour
Jocelyne Bloch
Grégoire Courtine
Marco Capogrosso
Recruitment of upper-limb motoneurons with epidural electrical stimulation of the cervical spinal cord
description The efficacy of epidural electrical stimulation (EES) to engage arm muscles and improve movement after spinal cord injury is still unclear. Here, the authors investigated how EES can recruit upper-limb motor neurons by combining computational modelling with experiments in non-human primates.
format article
author Nathan Greiner
Beatrice Barra
Giuseppe Schiavone
Henri Lorach
Nicholas James
Sara Conti
Melanie Kaeser
Florian Fallegger
Simon Borgognon
Stéphanie Lacour
Jocelyne Bloch
Grégoire Courtine
Marco Capogrosso
author_facet Nathan Greiner
Beatrice Barra
Giuseppe Schiavone
Henri Lorach
Nicholas James
Sara Conti
Melanie Kaeser
Florian Fallegger
Simon Borgognon
Stéphanie Lacour
Jocelyne Bloch
Grégoire Courtine
Marco Capogrosso
author_sort Nathan Greiner
title Recruitment of upper-limb motoneurons with epidural electrical stimulation of the cervical spinal cord
title_short Recruitment of upper-limb motoneurons with epidural electrical stimulation of the cervical spinal cord
title_full Recruitment of upper-limb motoneurons with epidural electrical stimulation of the cervical spinal cord
title_fullStr Recruitment of upper-limb motoneurons with epidural electrical stimulation of the cervical spinal cord
title_full_unstemmed Recruitment of upper-limb motoneurons with epidural electrical stimulation of the cervical spinal cord
title_sort recruitment of upper-limb motoneurons with epidural electrical stimulation of the cervical spinal cord
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/e2e43608aa6e42f2bb776ad62e0048f1
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