Safety and efficacy of laparoscopic repeat liver resection and re-operation for liver tumor

Abstract Laparoscopic liver resection (LLR) has been reported as a safe, minimally invasive, and effective surgery for the management of liver tumor. However, the efficacy and safety of laparoscopic repeat liver resection (LRLR) for recurrent liver tumor are unclear. Here, we analyzed the surgical r...

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Autores principales:	Koki Takase, Takuya Sakamoto, Yutaka Takeda, Yoshiaki Ohmura, Yoshiteru Katsura, Go Shinke, Kenji Kawai, Kohei Murakami, Yoshinori Kagawa, Toru Masuzawa, Atsushi Takeno, Taishi Hata, Kohei Murata
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/e2e4e0d2694342669bfd66f0dddfd169
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spelling	oai:doaj.org-article:e2e4e0d2694342669bfd66f0dddfd1692021-12-02T15:56:56ZSafety and efficacy of laparoscopic repeat liver resection and re-operation for liver tumor10.1038/s41598-021-89864-32045-2322https://doaj.org/article/e2e4e0d2694342669bfd66f0dddfd1692021-06-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-89864-3https://doaj.org/toc/2045-2322Abstract Laparoscopic liver resection (LLR) has been reported as a safe, minimally invasive, and effective surgery for the management of liver tumor. However, the efficacy and safety of laparoscopic repeat liver resection (LRLR) for recurrent liver tumor are unclear. Here, we analyzed the surgical results of LRLR. From June 2010 to May 2019, we performed 575 LLR surgeries in our department, and 454 of them underwent pure LLR for the single tumor. We classified the patients who received pure LLR for the single tumor into three groups: LRLR (n = 80), laparoscopic re-operation after previous abdominal surgery (LReOp; n = 136), and laparoscopic primary liver resection (LPLR; n = 238). We compared patient characteristics and surgical results between patients undergoing LRLR, LReOp and LPLR. We found no significant differences between LRLR and LPLR in the conversion rate to laparotomy (p = 0.8033), intraoperative bleeding (63.0 vs. 152.4 ml; p = 0.0911), or postoperative bile leakage rate (2.50 vs. 3.78%; p = 0.7367). We also found no significant difference in the surgical results between LReOp and LPLR. However, the number of patients undergoing the Pringle maneuver was lower in the LRLR group than the LPLR group (61.3 vs. 81.5%; p = 0.0004). This finding was more pronounced after open liver resection than laparoscopic liver resection (38.9 vs. 67.7%; p = 0.0270). The operative time was significantly longer in patients with proximity to previous cut surface than patients with no proximity to previous cut surface (307.4 vs. 235.7 min; p = 0.0201). LRLR can safely be performed with useful surgical results compared to LPLR.Koki TakaseTakuya SakamotoYutaka TakedaYoshiaki OhmuraYoshiteru KatsuraGo ShinkeKenji KawaiKohei MurakamiYoshinori KagawaToru MasuzawaAtsushi TakenoTaishi HataKohei MurataNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-7 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Koki Takase Takuya Sakamoto Yutaka Takeda Yoshiaki Ohmura Yoshiteru Katsura Go Shinke Kenji Kawai Kohei Murakami Yoshinori Kagawa Toru Masuzawa Atsushi Takeno Taishi Hata Kohei Murata Safety and efficacy of laparoscopic repeat liver resection and re-operation for liver tumor
description	Abstract Laparoscopic liver resection (LLR) has been reported as a safe, minimally invasive, and effective surgery for the management of liver tumor. However, the efficacy and safety of laparoscopic repeat liver resection (LRLR) for recurrent liver tumor are unclear. Here, we analyzed the surgical results of LRLR. From June 2010 to May 2019, we performed 575 LLR surgeries in our department, and 454 of them underwent pure LLR for the single tumor. We classified the patients who received pure LLR for the single tumor into three groups: LRLR (n = 80), laparoscopic re-operation after previous abdominal surgery (LReOp; n = 136), and laparoscopic primary liver resection (LPLR; n = 238). We compared patient characteristics and surgical results between patients undergoing LRLR, LReOp and LPLR. We found no significant differences between LRLR and LPLR in the conversion rate to laparotomy (p = 0.8033), intraoperative bleeding (63.0 vs. 152.4 ml; p = 0.0911), or postoperative bile leakage rate (2.50 vs. 3.78%; p = 0.7367). We also found no significant difference in the surgical results between LReOp and LPLR. However, the number of patients undergoing the Pringle maneuver was lower in the LRLR group than the LPLR group (61.3 vs. 81.5%; p = 0.0004). This finding was more pronounced after open liver resection than laparoscopic liver resection (38.9 vs. 67.7%; p = 0.0270). The operative time was significantly longer in patients with proximity to previous cut surface than patients with no proximity to previous cut surface (307.4 vs. 235.7 min; p = 0.0201). LRLR can safely be performed with useful surgical results compared to LPLR.
format	article
author	Koki Takase Takuya Sakamoto Yutaka Takeda Yoshiaki Ohmura Yoshiteru Katsura Go Shinke Kenji Kawai Kohei Murakami Yoshinori Kagawa Toru Masuzawa Atsushi Takeno Taishi Hata Kohei Murata
author_facet	Koki Takase Takuya Sakamoto Yutaka Takeda Yoshiaki Ohmura Yoshiteru Katsura Go Shinke Kenji Kawai Kohei Murakami Yoshinori Kagawa Toru Masuzawa Atsushi Takeno Taishi Hata Kohei Murata
author_sort	Koki Takase
title	Safety and efficacy of laparoscopic repeat liver resection and re-operation for liver tumor
title_short	Safety and efficacy of laparoscopic repeat liver resection and re-operation for liver tumor
title_full	Safety and efficacy of laparoscopic repeat liver resection and re-operation for liver tumor
title_fullStr	Safety and efficacy of laparoscopic repeat liver resection and re-operation for liver tumor
title_full_unstemmed	Safety and efficacy of laparoscopic repeat liver resection and re-operation for liver tumor
title_sort	safety and efficacy of laparoscopic repeat liver resection and re-operation for liver tumor
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/e2e4e0d2694342669bfd66f0dddfd169
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Safety and efficacy of laparoscopic repeat liver resection and re-operation for liver tumor

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