Phagocytosis is mediated by two-dimensional assemblies of the F-BAR protein GAS7

The Bin/Amphiphysin/Rvs167 (BAR) domain superfamily, which includes FCH-BAR (F-BAR) domain proteins are membrane-sculpting proteins. Here the authors combine a range of techniques and show that the F-BAR domain of growth-arrest specific protein 7 (GAS7) forms two-dimensional sheets on flat membranes...

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Autores principales: Kyoko Hanawa-Suetsugu, Yuzuru Itoh, Maisarah Ab Fatah, Tamako Nishimura, Kazuhiro Takemura, Kohei Takeshita, Satoru Kubota, Naoyuki Miyazaki, Wan Nurul Izzati Wan Mohamad Noor, Takehiko Inaba, Nhung Thi Hong Nguyen, Sayaka Hamada-Nakahara, Kayoko Oono-Yakura, Masashi Tachikawa, Kenji Iwasaki, Daisuke Kohda, Masaki Yamamoto, Akio Kitao, Atsushi Shimada, Shiro Suetsugu
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/e2ed47610d894146b620955e644b5a77
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spelling oai:doaj.org-article:e2ed47610d894146b620955e644b5a772021-12-02T15:35:49ZPhagocytosis is mediated by two-dimensional assemblies of the F-BAR protein GAS710.1038/s41467-019-12738-w2041-1723https://doaj.org/article/e2ed47610d894146b620955e644b5a772019-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-12738-whttps://doaj.org/toc/2041-1723The Bin/Amphiphysin/Rvs167 (BAR) domain superfamily, which includes FCH-BAR (F-BAR) domain proteins are membrane-sculpting proteins. Here the authors combine a range of techniques and show that the F-BAR domain of growth-arrest specific protein 7 (GAS7) forms two-dimensional sheets on flat membranes and that these oligomeric assemblies of GAS7 are required for the formation of phagocytic cups in macrophages.Kyoko Hanawa-SuetsuguYuzuru ItohMaisarah Ab FatahTamako NishimuraKazuhiro TakemuraKohei TakeshitaSatoru KubotaNaoyuki MiyazakiWan Nurul Izzati Wan Mohamad NoorTakehiko InabaNhung Thi Hong NguyenSayaka Hamada-NakaharaKayoko Oono-YakuraMasashi TachikawaKenji IwasakiDaisuke KohdaMasaki YamamotoAkio KitaoAtsushi ShimadaShiro SuetsuguNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Kyoko Hanawa-Suetsugu
Yuzuru Itoh
Maisarah Ab Fatah
Tamako Nishimura
Kazuhiro Takemura
Kohei Takeshita
Satoru Kubota
Naoyuki Miyazaki
Wan Nurul Izzati Wan Mohamad Noor
Takehiko Inaba
Nhung Thi Hong Nguyen
Sayaka Hamada-Nakahara
Kayoko Oono-Yakura
Masashi Tachikawa
Kenji Iwasaki
Daisuke Kohda
Masaki Yamamoto
Akio Kitao
Atsushi Shimada
Shiro Suetsugu
Phagocytosis is mediated by two-dimensional assemblies of the F-BAR protein GAS7
description The Bin/Amphiphysin/Rvs167 (BAR) domain superfamily, which includes FCH-BAR (F-BAR) domain proteins are membrane-sculpting proteins. Here the authors combine a range of techniques and show that the F-BAR domain of growth-arrest specific protein 7 (GAS7) forms two-dimensional sheets on flat membranes and that these oligomeric assemblies of GAS7 are required for the formation of phagocytic cups in macrophages.
format article
author Kyoko Hanawa-Suetsugu
Yuzuru Itoh
Maisarah Ab Fatah
Tamako Nishimura
Kazuhiro Takemura
Kohei Takeshita
Satoru Kubota
Naoyuki Miyazaki
Wan Nurul Izzati Wan Mohamad Noor
Takehiko Inaba
Nhung Thi Hong Nguyen
Sayaka Hamada-Nakahara
Kayoko Oono-Yakura
Masashi Tachikawa
Kenji Iwasaki
Daisuke Kohda
Masaki Yamamoto
Akio Kitao
Atsushi Shimada
Shiro Suetsugu
author_facet Kyoko Hanawa-Suetsugu
Yuzuru Itoh
Maisarah Ab Fatah
Tamako Nishimura
Kazuhiro Takemura
Kohei Takeshita
Satoru Kubota
Naoyuki Miyazaki
Wan Nurul Izzati Wan Mohamad Noor
Takehiko Inaba
Nhung Thi Hong Nguyen
Sayaka Hamada-Nakahara
Kayoko Oono-Yakura
Masashi Tachikawa
Kenji Iwasaki
Daisuke Kohda
Masaki Yamamoto
Akio Kitao
Atsushi Shimada
Shiro Suetsugu
author_sort Kyoko Hanawa-Suetsugu
title Phagocytosis is mediated by two-dimensional assemblies of the F-BAR protein GAS7
title_short Phagocytosis is mediated by two-dimensional assemblies of the F-BAR protein GAS7
title_full Phagocytosis is mediated by two-dimensional assemblies of the F-BAR protein GAS7
title_fullStr Phagocytosis is mediated by two-dimensional assemblies of the F-BAR protein GAS7
title_full_unstemmed Phagocytosis is mediated by two-dimensional assemblies of the F-BAR protein GAS7
title_sort phagocytosis is mediated by two-dimensional assemblies of the f-bar protein gas7
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/e2ed47610d894146b620955e644b5a77
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