Mucosal immunoglobulins at respiratory surfaces mark an ancient association that predates the emergence of tetrapods

In teleost fish the gills perform—in addition to respiration—functions such as immune defence. Here the authors show that IgT, a teleost specific Ig previously shown to be involved in gut and skin mucosal immunity, is locally induced in the gill, where it plays a key role in immunity in rainbow trou...

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Autores principales: Zhen Xu, Fumio Takizawa, David Parra, Daniela Gómez, Louise von Gersdorff Jørgensen, Scott E. LaPatra, J. Oriol Sunyer
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/e2efa59370b74f74bc9a7023d2bc5ed8
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Sumario:In teleost fish the gills perform—in addition to respiration—functions such as immune defence. Here the authors show that IgT, a teleost specific Ig previously shown to be involved in gut and skin mucosal immunity, is locally induced in the gill, where it plays a key role in immunity in rainbow trout.