Mucosal immunoglobulins at respiratory surfaces mark an ancient association that predates the emergence of tetrapods

In teleost fish the gills perform—in addition to respiration—functions such as immune defence. Here the authors show that IgT, a teleost specific Ig previously shown to be involved in gut and skin mucosal immunity, is locally induced in the gill, where it plays a key role in immunity in rainbow trou...

Full description

Saved in:
Bibliographic Details
Main Authors: Zhen Xu, Fumio Takizawa, David Parra, Daniela Gómez, Louise von Gersdorff Jørgensen, Scott E. LaPatra, J. Oriol Sunyer
Format: article
Language:EN
Published: Nature Portfolio 2016
Subjects:
Q
Online Access:https://doaj.org/article/e2efa59370b74f74bc9a7023d2bc5ed8
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:In teleost fish the gills perform—in addition to respiration—functions such as immune defence. Here the authors show that IgT, a teleost specific Ig previously shown to be involved in gut and skin mucosal immunity, is locally induced in the gill, where it plays a key role in immunity in rainbow trout.