Genome-wide functional analysis of phosphatases in the pathogenic fungus Cryptococcus neoformans

Genome-wide functional analysis of phosphatases in the pathogenic fungus Cryptococcus neoformans

Phosphatases are key components in cellular signalling networks. Here, the authors present a systematic functional analysis of phosphatases of the fungal pathogen Cryptococcus neoformans, revealing roles in virulence, stress responses, O-mannosylation, retromer function and other processes.

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Main Authors: Jae-Hyung Jin, Kyung-Tae Lee, Joohyeon Hong, Dongpil Lee, Eun-Ha Jang, Jin-Young Kim, Yeonseon Lee, Seung-Heon Lee, Yee-Seul So, Kwang-Woo Jung, Dong-Gi Lee, Eunji Jeong, Minjae Lee, Yu-Byeong Jang, Yeseul Choi, Myung Ha Lee, Ji-Seok Kim, Seong-Ryong Yu, Jin-Tae Choi, Jae-Won La, Haneul Choi, Sun-Woo Kim, Kyung Jin Seo, Yelin Lee, Eun Jung Thak, Jaeyoung Choi, Anna F. Averette, Yong-Hwan Lee, Joseph Heitman, Hyun Ah Kang, Eunji Cheong, Yong-Sun Bahn
Format: article
Language:EN
Published: Nature Portfolio 2020
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Science
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Online Access:https://doaj.org/article/e2f7a6bfdd5b4b528a41782645be312c
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Summary:Phosphatases are key components in cellular signalling networks. Here, the authors present a systematic functional analysis of phosphatases of the fungal pathogen Cryptococcus neoformans, revealing roles in virulence, stress responses, O-mannosylation, retromer function and other processes.

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