Genome-wide functional analysis of phosphatases in the pathogenic fungus Cryptococcus neoformans

Phosphatases are key components in cellular signalling networks. Here, the authors present a systematic functional analysis of phosphatases of the fungal pathogen Cryptococcus neoformans, revealing roles in virulence, stress responses, O-mannosylation, retromer function and other processes.

Guardado en:
Detalles Bibliográficos
Autores principales: Jae-Hyung Jin, Kyung-Tae Lee, Joohyeon Hong, Dongpil Lee, Eun-Ha Jang, Jin-Young Kim, Yeonseon Lee, Seung-Heon Lee, Yee-Seul So, Kwang-Woo Jung, Dong-Gi Lee, Eunji Jeong, Minjae Lee, Yu-Byeong Jang, Yeseul Choi, Myung Ha Lee, Ji-Seok Kim, Seong-Ryong Yu, Jin-Tae Choi, Jae-Won La, Haneul Choi, Sun-Woo Kim, Kyung Jin Seo, Yelin Lee, Eun Jung Thak, Jaeyoung Choi, Anna F. Averette, Yong-Hwan Lee, Joseph Heitman, Hyun Ah Kang, Eunji Cheong, Yong-Sun Bahn
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
Materias:
Q
Acceso en línea:https://doaj.org/article/e2f7a6bfdd5b4b528a41782645be312c
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
id oai:doaj.org-article:e2f7a6bfdd5b4b528a41782645be312c
record_format dspace
spelling oai:doaj.org-article:e2f7a6bfdd5b4b528a41782645be312c2021-12-02T15:09:10ZGenome-wide functional analysis of phosphatases in the pathogenic fungus Cryptococcus neoformans10.1038/s41467-020-18028-02041-1723https://doaj.org/article/e2f7a6bfdd5b4b528a41782645be312c2020-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-18028-0https://doaj.org/toc/2041-1723Phosphatases are key components in cellular signalling networks. Here, the authors present a systematic functional analysis of phosphatases of the fungal pathogen Cryptococcus neoformans, revealing roles in virulence, stress responses, O-mannosylation, retromer function and other processes.Jae-Hyung JinKyung-Tae LeeJoohyeon HongDongpil LeeEun-Ha JangJin-Young KimYeonseon LeeSeung-Heon LeeYee-Seul SoKwang-Woo JungDong-Gi LeeEunji JeongMinjae LeeYu-Byeong JangYeseul ChoiMyung Ha LeeJi-Seok KimSeong-Ryong YuJin-Tae ChoiJae-Won LaHaneul ChoiSun-Woo KimKyung Jin SeoYelin LeeEun Jung ThakJaeyoung ChoiAnna F. AveretteYong-Hwan LeeJoseph HeitmanHyun Ah KangEunji CheongYong-Sun BahnNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Jae-Hyung Jin
Kyung-Tae Lee
Joohyeon Hong
Dongpil Lee
Eun-Ha Jang
Jin-Young Kim
Yeonseon Lee
Seung-Heon Lee
Yee-Seul So
Kwang-Woo Jung
Dong-Gi Lee
Eunji Jeong
Minjae Lee
Yu-Byeong Jang
Yeseul Choi
Myung Ha Lee
Ji-Seok Kim
Seong-Ryong Yu
Jin-Tae Choi
Jae-Won La
Haneul Choi
Sun-Woo Kim
Kyung Jin Seo
Yelin Lee
Eun Jung Thak
Jaeyoung Choi
Anna F. Averette
Yong-Hwan Lee
Joseph Heitman
Hyun Ah Kang
Eunji Cheong
Yong-Sun Bahn
Genome-wide functional analysis of phosphatases in the pathogenic fungus Cryptococcus neoformans
description Phosphatases are key components in cellular signalling networks. Here, the authors present a systematic functional analysis of phosphatases of the fungal pathogen Cryptococcus neoformans, revealing roles in virulence, stress responses, O-mannosylation, retromer function and other processes.
format article
author Jae-Hyung Jin
Kyung-Tae Lee
Joohyeon Hong
Dongpil Lee
Eun-Ha Jang
Jin-Young Kim
Yeonseon Lee
Seung-Heon Lee
Yee-Seul So
Kwang-Woo Jung
Dong-Gi Lee
Eunji Jeong
Minjae Lee
Yu-Byeong Jang
Yeseul Choi
Myung Ha Lee
Ji-Seok Kim
Seong-Ryong Yu
Jin-Tae Choi
Jae-Won La
Haneul Choi
Sun-Woo Kim
Kyung Jin Seo
Yelin Lee
Eun Jung Thak
Jaeyoung Choi
Anna F. Averette
Yong-Hwan Lee
Joseph Heitman
Hyun Ah Kang
Eunji Cheong
Yong-Sun Bahn
author_facet Jae-Hyung Jin
Kyung-Tae Lee
Joohyeon Hong
Dongpil Lee
Eun-Ha Jang
Jin-Young Kim
Yeonseon Lee
Seung-Heon Lee
Yee-Seul So
Kwang-Woo Jung
Dong-Gi Lee
Eunji Jeong
Minjae Lee
Yu-Byeong Jang
Yeseul Choi
Myung Ha Lee
Ji-Seok Kim
Seong-Ryong Yu
Jin-Tae Choi
Jae-Won La
Haneul Choi
Sun-Woo Kim
Kyung Jin Seo
Yelin Lee
Eun Jung Thak
Jaeyoung Choi
Anna F. Averette
Yong-Hwan Lee
Joseph Heitman
Hyun Ah Kang
Eunji Cheong
Yong-Sun Bahn
author_sort Jae-Hyung Jin
title Genome-wide functional analysis of phosphatases in the pathogenic fungus Cryptococcus neoformans
title_short Genome-wide functional analysis of phosphatases in the pathogenic fungus Cryptococcus neoformans
title_full Genome-wide functional analysis of phosphatases in the pathogenic fungus Cryptococcus neoformans
title_fullStr Genome-wide functional analysis of phosphatases in the pathogenic fungus Cryptococcus neoformans
title_full_unstemmed Genome-wide functional analysis of phosphatases in the pathogenic fungus Cryptococcus neoformans
title_sort genome-wide functional analysis of phosphatases in the pathogenic fungus cryptococcus neoformans
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/e2f7a6bfdd5b4b528a41782645be312c
work_keys_str_mv AT jaehyungjin genomewidefunctionalanalysisofphosphatasesinthepathogenicfunguscryptococcusneoformans
AT kyungtaelee genomewidefunctionalanalysisofphosphatasesinthepathogenicfunguscryptococcusneoformans
AT joohyeonhong genomewidefunctionalanalysisofphosphatasesinthepathogenicfunguscryptococcusneoformans
AT dongpillee genomewidefunctionalanalysisofphosphatasesinthepathogenicfunguscryptococcusneoformans
AT eunhajang genomewidefunctionalanalysisofphosphatasesinthepathogenicfunguscryptococcusneoformans
AT jinyoungkim genomewidefunctionalanalysisofphosphatasesinthepathogenicfunguscryptococcusneoformans
AT yeonseonlee genomewidefunctionalanalysisofphosphatasesinthepathogenicfunguscryptococcusneoformans
AT seungheonlee genomewidefunctionalanalysisofphosphatasesinthepathogenicfunguscryptococcusneoformans
AT yeeseulso genomewidefunctionalanalysisofphosphatasesinthepathogenicfunguscryptococcusneoformans
AT kwangwoojung genomewidefunctionalanalysisofphosphatasesinthepathogenicfunguscryptococcusneoformans
AT donggilee genomewidefunctionalanalysisofphosphatasesinthepathogenicfunguscryptococcusneoformans
AT eunjijeong genomewidefunctionalanalysisofphosphatasesinthepathogenicfunguscryptococcusneoformans
AT minjaelee genomewidefunctionalanalysisofphosphatasesinthepathogenicfunguscryptococcusneoformans
AT yubyeongjang genomewidefunctionalanalysisofphosphatasesinthepathogenicfunguscryptococcusneoformans
AT yeseulchoi genomewidefunctionalanalysisofphosphatasesinthepathogenicfunguscryptococcusneoformans
AT myunghalee genomewidefunctionalanalysisofphosphatasesinthepathogenicfunguscryptococcusneoformans
AT jiseokkim genomewidefunctionalanalysisofphosphatasesinthepathogenicfunguscryptococcusneoformans
AT seongryongyu genomewidefunctionalanalysisofphosphatasesinthepathogenicfunguscryptococcusneoformans
AT jintaechoi genomewidefunctionalanalysisofphosphatasesinthepathogenicfunguscryptococcusneoformans
AT jaewonla genomewidefunctionalanalysisofphosphatasesinthepathogenicfunguscryptococcusneoformans
AT haneulchoi genomewidefunctionalanalysisofphosphatasesinthepathogenicfunguscryptococcusneoformans
AT sunwookim genomewidefunctionalanalysisofphosphatasesinthepathogenicfunguscryptococcusneoformans
AT kyungjinseo genomewidefunctionalanalysisofphosphatasesinthepathogenicfunguscryptococcusneoformans
AT yelinlee genomewidefunctionalanalysisofphosphatasesinthepathogenicfunguscryptococcusneoformans
AT eunjungthak genomewidefunctionalanalysisofphosphatasesinthepathogenicfunguscryptococcusneoformans
AT jaeyoungchoi genomewidefunctionalanalysisofphosphatasesinthepathogenicfunguscryptococcusneoformans
AT annafaverette genomewidefunctionalanalysisofphosphatasesinthepathogenicfunguscryptococcusneoformans
AT yonghwanlee genomewidefunctionalanalysisofphosphatasesinthepathogenicfunguscryptococcusneoformans
AT josephheitman genomewidefunctionalanalysisofphosphatasesinthepathogenicfunguscryptococcusneoformans
AT hyunahkang genomewidefunctionalanalysisofphosphatasesinthepathogenicfunguscryptococcusneoformans
AT eunjicheong genomewidefunctionalanalysisofphosphatasesinthepathogenicfunguscryptococcusneoformans
AT yongsunbahn genomewidefunctionalanalysisofphosphatasesinthepathogenicfunguscryptococcusneoformans
_version_ 1718387908349526016