Genome-wide functional analysis of phosphatases in the pathogenic fungus Cryptococcus neoformans
Phosphatases are key components in cellular signalling networks. Here, the authors present a systematic functional analysis of phosphatases of the fungal pathogen Cryptococcus neoformans, revealing roles in virulence, stress responses, O-mannosylation, retromer function and other processes.
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2020
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oai:doaj.org-article:e2f7a6bfdd5b4b528a41782645be312c2021-12-02T15:09:10ZGenome-wide functional analysis of phosphatases in the pathogenic fungus Cryptococcus neoformans10.1038/s41467-020-18028-02041-1723https://doaj.org/article/e2f7a6bfdd5b4b528a41782645be312c2020-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-18028-0https://doaj.org/toc/2041-1723Phosphatases are key components in cellular signalling networks. Here, the authors present a systematic functional analysis of phosphatases of the fungal pathogen Cryptococcus neoformans, revealing roles in virulence, stress responses, O-mannosylation, retromer function and other processes.Jae-Hyung JinKyung-Tae LeeJoohyeon HongDongpil LeeEun-Ha JangJin-Young KimYeonseon LeeSeung-Heon LeeYee-Seul SoKwang-Woo JungDong-Gi LeeEunji JeongMinjae LeeYu-Byeong JangYeseul ChoiMyung Ha LeeJi-Seok KimSeong-Ryong YuJin-Tae ChoiJae-Won LaHaneul ChoiSun-Woo KimKyung Jin SeoYelin LeeEun Jung ThakJaeyoung ChoiAnna F. AveretteYong-Hwan LeeJoseph HeitmanHyun Ah KangEunji CheongYong-Sun BahnNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-17 (2020) |
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Science Q Jae-Hyung Jin Kyung-Tae Lee Joohyeon Hong Dongpil Lee Eun-Ha Jang Jin-Young Kim Yeonseon Lee Seung-Heon Lee Yee-Seul So Kwang-Woo Jung Dong-Gi Lee Eunji Jeong Minjae Lee Yu-Byeong Jang Yeseul Choi Myung Ha Lee Ji-Seok Kim Seong-Ryong Yu Jin-Tae Choi Jae-Won La Haneul Choi Sun-Woo Kim Kyung Jin Seo Yelin Lee Eun Jung Thak Jaeyoung Choi Anna F. Averette Yong-Hwan Lee Joseph Heitman Hyun Ah Kang Eunji Cheong Yong-Sun Bahn Genome-wide functional analysis of phosphatases in the pathogenic fungus Cryptococcus neoformans |
description |
Phosphatases are key components in cellular signalling networks. Here, the authors present a systematic functional analysis of phosphatases of the fungal pathogen Cryptococcus neoformans, revealing roles in virulence, stress responses, O-mannosylation, retromer function and other processes. |
format |
article |
author |
Jae-Hyung Jin Kyung-Tae Lee Joohyeon Hong Dongpil Lee Eun-Ha Jang Jin-Young Kim Yeonseon Lee Seung-Heon Lee Yee-Seul So Kwang-Woo Jung Dong-Gi Lee Eunji Jeong Minjae Lee Yu-Byeong Jang Yeseul Choi Myung Ha Lee Ji-Seok Kim Seong-Ryong Yu Jin-Tae Choi Jae-Won La Haneul Choi Sun-Woo Kim Kyung Jin Seo Yelin Lee Eun Jung Thak Jaeyoung Choi Anna F. Averette Yong-Hwan Lee Joseph Heitman Hyun Ah Kang Eunji Cheong Yong-Sun Bahn |
author_facet |
Jae-Hyung Jin Kyung-Tae Lee Joohyeon Hong Dongpil Lee Eun-Ha Jang Jin-Young Kim Yeonseon Lee Seung-Heon Lee Yee-Seul So Kwang-Woo Jung Dong-Gi Lee Eunji Jeong Minjae Lee Yu-Byeong Jang Yeseul Choi Myung Ha Lee Ji-Seok Kim Seong-Ryong Yu Jin-Tae Choi Jae-Won La Haneul Choi Sun-Woo Kim Kyung Jin Seo Yelin Lee Eun Jung Thak Jaeyoung Choi Anna F. Averette Yong-Hwan Lee Joseph Heitman Hyun Ah Kang Eunji Cheong Yong-Sun Bahn |
author_sort |
Jae-Hyung Jin |
title |
Genome-wide functional analysis of phosphatases in the pathogenic fungus Cryptococcus neoformans |
title_short |
Genome-wide functional analysis of phosphatases in the pathogenic fungus Cryptococcus neoformans |
title_full |
Genome-wide functional analysis of phosphatases in the pathogenic fungus Cryptococcus neoformans |
title_fullStr |
Genome-wide functional analysis of phosphatases in the pathogenic fungus Cryptococcus neoformans |
title_full_unstemmed |
Genome-wide functional analysis of phosphatases in the pathogenic fungus Cryptococcus neoformans |
title_sort |
genome-wide functional analysis of phosphatases in the pathogenic fungus cryptococcus neoformans |
publisher |
Nature Portfolio |
publishDate |
2020 |
url |
https://doaj.org/article/e2f7a6bfdd5b4b528a41782645be312c |
work_keys_str_mv |
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