Cep55 promotes cytokinesis of neural progenitors but is dispensable for most mammalian cell divisions

In mammalian cell lines, Cep55 protein recruits the endosomal sorting complex required for transport (ESCRT) and promotes the completion of cell division. Here, the authors show that Cep55-knockout mice are viable and primary fibroblasts cultured in vitro divide in a Cep55 and ESCRT-independent way.

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Main Authors:	Antonio Tedeschi, Jorge Almagro, Matthew J. Renshaw, Hendrik A. Messal, Axel Behrens, Mark Petronczki
Format:	article
Language:	EN
Published:	Nature Portfolio 2020
Subjects:	Science Q
Online Access:	https://doaj.org/article/e2f8bae001274af3b17c7fac1e5e07b8
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spelling	oai:doaj.org-article:e2f8bae001274af3b17c7fac1e5e07b82021-12-02T15:34:34ZCep55 promotes cytokinesis of neural progenitors but is dispensable for most mammalian cell divisions10.1038/s41467-020-15359-w2041-1723https://doaj.org/article/e2f8bae001274af3b17c7fac1e5e07b82020-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-15359-whttps://doaj.org/toc/2041-1723In mammalian cell lines, Cep55 protein recruits the endosomal sorting complex required for transport (ESCRT) and promotes the completion of cell division. Here, the authors show that Cep55-knockout mice are viable and primary fibroblasts cultured in vitro divide in a Cep55 and ESCRT-independent way.Antonio TedeschiJorge AlmagroMatthew J. RenshawHendrik A. MessalAxel BehrensMark PetronczkiNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Antonio Tedeschi Jorge Almagro Matthew J. Renshaw Hendrik A. Messal Axel Behrens Mark Petronczki Cep55 promotes cytokinesis of neural progenitors but is dispensable for most mammalian cell divisions
description	In mammalian cell lines, Cep55 protein recruits the endosomal sorting complex required for transport (ESCRT) and promotes the completion of cell division. Here, the authors show that Cep55-knockout mice are viable and primary fibroblasts cultured in vitro divide in a Cep55 and ESCRT-independent way.
format	article
author	Antonio Tedeschi Jorge Almagro Matthew J. Renshaw Hendrik A. Messal Axel Behrens Mark Petronczki
author_facet	Antonio Tedeschi Jorge Almagro Matthew J. Renshaw Hendrik A. Messal Axel Behrens Mark Petronczki
author_sort	Antonio Tedeschi
title	Cep55 promotes cytokinesis of neural progenitors but is dispensable for most mammalian cell divisions
title_short	Cep55 promotes cytokinesis of neural progenitors but is dispensable for most mammalian cell divisions
title_full	Cep55 promotes cytokinesis of neural progenitors but is dispensable for most mammalian cell divisions
title_fullStr	Cep55 promotes cytokinesis of neural progenitors but is dispensable for most mammalian cell divisions
title_full_unstemmed	Cep55 promotes cytokinesis of neural progenitors but is dispensable for most mammalian cell divisions
title_sort	cep55 promotes cytokinesis of neural progenitors but is dispensable for most mammalian cell divisions
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/e2f8bae001274af3b17c7fac1e5e07b8
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Cep55 promotes cytokinesis of neural progenitors but is dispensable for most mammalian cell divisions

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