COMPARISON OF HEMODYNAMIC STABILITY WITH CISATRACURIUM AND ATRACURIUM IN PATIENTS WITH LOW EJECTION FRACTION UNDERGOING CORONARY ARTERY BYPASS GRAFTING

Objective: To compare the hemodynamic stability with cisatracurium and atracurium in patients with low ejection fraction undergoing coronary artery bypass grafting. Study Design: Randomized controlled trial. Place and Duration of Study: Department of Anesthesiology, Army Cardiac Center, Lahore...

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Autores principales:	Mehwish Naseer, Imran Bashir, Vaqar Ilahi Paracha, Kaleem Ahmad, Imtiaz Ahmed Chaudhry, Tahseen Ahmed
Formato:	article
Lenguaje:	EN
Publicado:	Army Medical College Rawalpindi 2020
Materias:	atracurium cisatracurium coronary artery bypass grafting ejection fraction hemodynamic Medicine R Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/e2fbfea5495e4eae9c80ea635d3bbd18
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spelling	oai:doaj.org-article:e2fbfea5495e4eae9c80ea635d3bbd182021-12-02T19:11:39ZCOMPARISON OF HEMODYNAMIC STABILITY WITH CISATRACURIUM AND ATRACURIUM IN PATIENTS WITH LOW EJECTION FRACTION UNDERGOING CORONARY ARTERY BYPASS GRAFTINGdoi.org/10.51253/pafmj.v70iSuppl-4.60040030-96482411-8842https://doaj.org/article/e2fbfea5495e4eae9c80ea635d3bbd182020-12-01T00:00:00Zhttps://pafmj.org/index.php/PAFMJ/article/view/6004https://doaj.org/toc/0030-9648https://doaj.org/toc/2411-8842Objective: To compare the hemodynamic stability with cisatracurium and atracurium in patients with low ejection fraction undergoing coronary artery bypass grafting. Study Design: Randomized controlled trial. Place and Duration of Study: Department of Anesthesiology, Army Cardiac Center, Lahore, from Jan 2018 to Nov 2018. Methodology: A total of 80 adult patients were recruited or invited to participate in this study. Further the cohort was divided in to two groups with respect to their treatment by draw method. Group I contained a total of 40 patients, which were given Cisatracurium 0.2mg/kg at induction of anesthesia. The group II patients constitute the same number but the treatment medication given was 0.5mg/kg Atracurium at induction. Results: Before anesthesia induction, pulse rate was 84.10 ± 5.54 bpm and 83.01 ± 5.72 bpm in group A and B, respectively (p=0.385). At 4 minutes after anesthesia induction, pulse rate was 83.05 ± 5.58 bpm and 86.37 ± 6.62 bpm in group A and B, respectively (p=0.017). Before anesthesia induction, mean arterial pressure was 71.07 ± 7.62 mmHg and 69.22 ± 10.77 mmHg in group A and B, respectively (p=0.378). At 4 minutes after anesthesia induction, mean arterial pressure was 68.22 ± 8.17 mmHg and 72.20 ± 8.09 mmHg in group A and B, respectively (p=0.032) table-II. Conclusion: We may conclude from our study that although there is significant difference of the change in arterial blood pressure due to the both drugs. The group A was having more stable hemodynamic indexes where the drug administrated was Cisatracurium.Mehwish NaseerImran BashirVaqar Ilahi ParachaKaleem AhmadImtiaz Ahmed ChaudhryTahseen AhmedArmy Medical College Rawalpindiarticleatracuriumcisatracuriumcoronary artery bypass graftingejection fractionhemodynamicMedicineRMedicine (General)R5-920ENPakistan Armed Forces Medical Journal, Vol 70, Iss 4, Pp 706-709 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	atracurium cisatracurium coronary artery bypass grafting ejection fraction hemodynamic Medicine R Medicine (General) R5-920
spellingShingle	atracurium cisatracurium coronary artery bypass grafting ejection fraction hemodynamic Medicine R Medicine (General) R5-920 Mehwish Naseer Imran Bashir Vaqar Ilahi Paracha Kaleem Ahmad Imtiaz Ahmed Chaudhry Tahseen Ahmed COMPARISON OF HEMODYNAMIC STABILITY WITH CISATRACURIUM AND ATRACURIUM IN PATIENTS WITH LOW EJECTION FRACTION UNDERGOING CORONARY ARTERY BYPASS GRAFTING
description	Objective: To compare the hemodynamic stability with cisatracurium and atracurium in patients with low ejection fraction undergoing coronary artery bypass grafting. Study Design: Randomized controlled trial. Place and Duration of Study: Department of Anesthesiology, Army Cardiac Center, Lahore, from Jan 2018 to Nov 2018. Methodology: A total of 80 adult patients were recruited or invited to participate in this study. Further the cohort was divided in to two groups with respect to their treatment by draw method. Group I contained a total of 40 patients, which were given Cisatracurium 0.2mg/kg at induction of anesthesia. The group II patients constitute the same number but the treatment medication given was 0.5mg/kg Atracurium at induction. Results: Before anesthesia induction, pulse rate was 84.10 ± 5.54 bpm and 83.01 ± 5.72 bpm in group A and B, respectively (p=0.385). At 4 minutes after anesthesia induction, pulse rate was 83.05 ± 5.58 bpm and 86.37 ± 6.62 bpm in group A and B, respectively (p=0.017). Before anesthesia induction, mean arterial pressure was 71.07 ± 7.62 mmHg and 69.22 ± 10.77 mmHg in group A and B, respectively (p=0.378). At 4 minutes after anesthesia induction, mean arterial pressure was 68.22 ± 8.17 mmHg and 72.20 ± 8.09 mmHg in group A and B, respectively (p=0.032) table-II. Conclusion: We may conclude from our study that although there is significant difference of the change in arterial blood pressure due to the both drugs. The group A was having more stable hemodynamic indexes where the drug administrated was Cisatracurium.
format	article
author	Mehwish Naseer Imran Bashir Vaqar Ilahi Paracha Kaleem Ahmad Imtiaz Ahmed Chaudhry Tahseen Ahmed
author_facet	Mehwish Naseer Imran Bashir Vaqar Ilahi Paracha Kaleem Ahmad Imtiaz Ahmed Chaudhry Tahseen Ahmed
author_sort	Mehwish Naseer
title	COMPARISON OF HEMODYNAMIC STABILITY WITH CISATRACURIUM AND ATRACURIUM IN PATIENTS WITH LOW EJECTION FRACTION UNDERGOING CORONARY ARTERY BYPASS GRAFTING
title_short	COMPARISON OF HEMODYNAMIC STABILITY WITH CISATRACURIUM AND ATRACURIUM IN PATIENTS WITH LOW EJECTION FRACTION UNDERGOING CORONARY ARTERY BYPASS GRAFTING
title_full	COMPARISON OF HEMODYNAMIC STABILITY WITH CISATRACURIUM AND ATRACURIUM IN PATIENTS WITH LOW EJECTION FRACTION UNDERGOING CORONARY ARTERY BYPASS GRAFTING
title_fullStr	COMPARISON OF HEMODYNAMIC STABILITY WITH CISATRACURIUM AND ATRACURIUM IN PATIENTS WITH LOW EJECTION FRACTION UNDERGOING CORONARY ARTERY BYPASS GRAFTING
title_full_unstemmed	COMPARISON OF HEMODYNAMIC STABILITY WITH CISATRACURIUM AND ATRACURIUM IN PATIENTS WITH LOW EJECTION FRACTION UNDERGOING CORONARY ARTERY BYPASS GRAFTING
title_sort	comparison of hemodynamic stability with cisatracurium and atracurium in patients with low ejection fraction undergoing coronary artery bypass grafting
publisher	Army Medical College Rawalpindi
publishDate	2020
url	https://doaj.org/article/e2fbfea5495e4eae9c80ea635d3bbd18
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COMPARISON OF HEMODYNAMIC STABILITY WITH CISATRACURIUM AND ATRACURIUM IN PATIENTS WITH LOW EJECTION FRACTION UNDERGOING CORONARY ARTERY BYPASS GRAFTING

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