Human Cytomegalovirus miR-US5-2 Downregulation of GAB1 Regulates Cellular Proliferation and <italic toggle="yes">UL138</italic> Expression through Modulation of Epidermal Growth Factor Receptor Signaling Pathways

Human Cytomegalovirus miR-US5-2 Downregulation of GAB1 Regulates Cellular Proliferation and <italic toggle="yes">UL138</italic> Expression through Modulation of Epidermal Growth Factor Receptor Signaling Pathways

ABSTRACT Regulation of epidermal growth factor (EGF) receptor (EGFR) signaling is critical for the replication of human cytomegalovirus (HCMV) as well as latency and reactivation in CD34+ hematopoietic progenitor cells. HCMV microRNAs (miRNAs) provide a means to modulate the signaling activated by E...

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Autores principales: Meaghan H. Hancock, Jennifer Mitchell, Felicia D. Goodrum, Jay A. Nelson
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2020
Materias:
GAB1
UL138
cytomegalovirus
miRNA
Microbiology
QR1-502
Acceso en línea:https://doaj.org/article/e2fc9318c32f4c518a32c8f411179a7e
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