Mediator subunit 12 is required for neutrophil development in zebrafish.

Hematopoiesis requires the spatiotemporal organization of regulatory factors to successfully orchestrate diverse lineage specificity from stem and progenitor cells. Med12 is a regulatory component of the large Mediator complex that enables contact between the general RNA polymerase II transcriptiona...

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Autores principales: Maria-Cristina Keightley, Judith E Layton, John W Hayman, Joan K Heath, Graham J Lieschke
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2011
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Acceso en línea:https://doaj.org/article/e3049a45bf784fce84b80aff8f00f856
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