Preparing anti-SARS-CoV-2 agent EIDD-2801 by a practical and scalable approach, and quick evaluation via machine learning

EIDD-2801 is an orally bioavailable prodrug, which will be applied for emergency use authorization from the U.S. Food and Drug Administration for the treatment of COVID-19. To investigate the optimal parameters, EIDD-2801 was optimized via a four-step synthesis with high purity of 99.9%. The hydroxy...

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Autores principales: Zhen Qin, Bin Dong, Renbing Wang, Dechun Huang, Jubo Wang, Xi Feng, Jinlei Bian, Zhiyu Li
Formato: article
Lenguaje:EN
Publicado: Elsevier 2021
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Acceso en línea:https://doaj.org/article/e311f1d537714e31bf747cecb30787ef
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