The essential role of PRAK in tumor metastasis and its therapeutic potential

The essential role of PRAK in tumor metastasis and its therapeutic potential

Metastasis is one of the leading causes of cancer-related death. Here, the authors report a pro-metastatic role of PRAK in breast cancer lung metastasis via a mechanism involving enhanced HIF-1α translation, and propose PRAK targeting as a strategy to treat metastasis.

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Bibliographic Details
Main Authors: Yuqing Wang, Wei Wang, Haoming Wu, Yu Zhou, Xiaodan Qin, Yan Wang, Jia Wu, Xiu-Yuan Sun, Yan Yang, Hui Xu, Xiaoping Qian, Xuewen Pang, Yan Li, Zhiqian Zhang, Jiahuai Han, Yu Zhang
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
Science
Q
Online Access:https://doaj.org/article/e316bbbf766c4207a4ac09e31608be76
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https://doaj.org/article/e316bbbf766c4207a4ac09e31608be76

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