ATAC-seq footprinting unravels kinetics of transcription factor binding during zygotic genome activation

Footprinting analysis allows genome-wide investigation of transcription factor (TF) binding on chromatin. Here the authors developed a framework termed TOBIAS aimed at identifying footprints of chromatin-associated proteins from ATAC-seq accessibility profiles and apply it to zygotic development dat...

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Autores principales:	Mette Bentsen, Philipp Goymann, Hendrik Schultheis, Kathrin Klee, Anastasiia Petrova, René Wiegandt, Annika Fust, Jens Preussner, Carsten Kuenne, Thomas Braun, Johnny Kim, Mario Looso
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/e3286bfee3c34ca8982de7e68a99c0a2
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spelling	oai:doaj.org-article:e3286bfee3c34ca8982de7e68a99c0a22021-12-02T16:35:00ZATAC-seq footprinting unravels kinetics of transcription factor binding during zygotic genome activation10.1038/s41467-020-18035-12041-1723https://doaj.org/article/e3286bfee3c34ca8982de7e68a99c0a22020-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-18035-1https://doaj.org/toc/2041-1723Footprinting analysis allows genome-wide investigation of transcription factor (TF) binding on chromatin. Here the authors developed a framework termed TOBIAS aimed at identifying footprints of chromatin-associated proteins from ATAC-seq accessibility profiles and apply it to zygotic development datasets.Mette BentsenPhilipp GoymannHendrik SchultheisKathrin KleeAnastasiia PetrovaRené WiegandtAnnika FustJens PreussnerCarsten KuenneThomas BraunJohnny KimMario LoosoNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Mette Bentsen Philipp Goymann Hendrik Schultheis Kathrin Klee Anastasiia Petrova René Wiegandt Annika Fust Jens Preussner Carsten Kuenne Thomas Braun Johnny Kim Mario Looso ATAC-seq footprinting unravels kinetics of transcription factor binding during zygotic genome activation
description	Footprinting analysis allows genome-wide investigation of transcription factor (TF) binding on chromatin. Here the authors developed a framework termed TOBIAS aimed at identifying footprints of chromatin-associated proteins from ATAC-seq accessibility profiles and apply it to zygotic development datasets.
format	article
author	Mette Bentsen Philipp Goymann Hendrik Schultheis Kathrin Klee Anastasiia Petrova René Wiegandt Annika Fust Jens Preussner Carsten Kuenne Thomas Braun Johnny Kim Mario Looso
author_facet	Mette Bentsen Philipp Goymann Hendrik Schultheis Kathrin Klee Anastasiia Petrova René Wiegandt Annika Fust Jens Preussner Carsten Kuenne Thomas Braun Johnny Kim Mario Looso
author_sort	Mette Bentsen
title	ATAC-seq footprinting unravels kinetics of transcription factor binding during zygotic genome activation
title_short	ATAC-seq footprinting unravels kinetics of transcription factor binding during zygotic genome activation
title_full	ATAC-seq footprinting unravels kinetics of transcription factor binding during zygotic genome activation
title_fullStr	ATAC-seq footprinting unravels kinetics of transcription factor binding during zygotic genome activation
title_full_unstemmed	ATAC-seq footprinting unravels kinetics of transcription factor binding during zygotic genome activation
title_sort	atac-seq footprinting unravels kinetics of transcription factor binding during zygotic genome activation
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/e3286bfee3c34ca8982de7e68a99c0a2
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ATAC-seq footprinting unravels kinetics of transcription factor binding during zygotic genome activation

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