Characterization of the enhancer and promoter landscape of inflammatory bowel disease from human colon biopsies

Many SNPs associated with inflammatory bowel disease are located in non-coding genomic regions. Here, the authors perform CAGE-sequencing on descending colon biopsies of Crohn’s disease and ulcerative colitis patients to map transcription start sites and enhancer activity for analysis of regulatory...

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Autores principales:	Mette Boyd, Malte Thodberg, Morana Vitezic, Jette Bornholdt, Kristoffer Vitting-Seerup, Yun Chen, Mehmet Coskun, Yuan Li, Bobby Zhao Sheng Lo, Pia Klausen, Pawel Jan Schweiger, Anders Gorm Pedersen, Nicolas Rapin, Kerstin Skovgaard, Katja Dahlgaard, Robin Andersson, Thilde Bagger Terkelsen, Berit Lilje, Jesper Thorvald Troelsen, Andreas Munk Petersen, Kim Bak Jensen, Ismail Gögenur, Peter Thielsen, Jakob Benedict Seidelin, Ole Haagen Nielsen, Jacob Tveiten Bjerrum, Albin Sandelin
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/e32e0b001f3f40cfa76d4515cf61a036
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spelling	oai:doaj.org-article:e32e0b001f3f40cfa76d4515cf61a0362021-12-02T14:38:47ZCharacterization of the enhancer and promoter landscape of inflammatory bowel disease from human colon biopsies10.1038/s41467-018-03766-z2041-1723https://doaj.org/article/e32e0b001f3f40cfa76d4515cf61a0362018-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-03766-zhttps://doaj.org/toc/2041-1723Many SNPs associated with inflammatory bowel disease are located in non-coding genomic regions. Here, the authors perform CAGE-sequencing on descending colon biopsies of Crohn’s disease and ulcerative colitis patients to map transcription start sites and enhancer activity for analysis of regulatory regions.Mette BoydMalte ThodbergMorana VitezicJette BornholdtKristoffer Vitting-SeerupYun ChenMehmet CoskunYuan LiBobby Zhao Sheng LoPia KlausenPawel Jan SchweigerAnders Gorm PedersenNicolas RapinKerstin SkovgaardKatja DahlgaardRobin AnderssonThilde Bagger TerkelsenBerit LiljeJesper Thorvald TroelsenAndreas Munk PetersenKim Bak JensenIsmail GögenurPeter ThielsenJakob Benedict SeidelinOle Haagen NielsenJacob Tveiten BjerrumAlbin SandelinNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-19 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Mette Boyd Malte Thodberg Morana Vitezic Jette Bornholdt Kristoffer Vitting-Seerup Yun Chen Mehmet Coskun Yuan Li Bobby Zhao Sheng Lo Pia Klausen Pawel Jan Schweiger Anders Gorm Pedersen Nicolas Rapin Kerstin Skovgaard Katja Dahlgaard Robin Andersson Thilde Bagger Terkelsen Berit Lilje Jesper Thorvald Troelsen Andreas Munk Petersen Kim Bak Jensen Ismail Gögenur Peter Thielsen Jakob Benedict Seidelin Ole Haagen Nielsen Jacob Tveiten Bjerrum Albin Sandelin Characterization of the enhancer and promoter landscape of inflammatory bowel disease from human colon biopsies
description	Many SNPs associated with inflammatory bowel disease are located in non-coding genomic regions. Here, the authors perform CAGE-sequencing on descending colon biopsies of Crohn’s disease and ulcerative colitis patients to map transcription start sites and enhancer activity for analysis of regulatory regions.
format	article
author	Mette Boyd Malte Thodberg Morana Vitezic Jette Bornholdt Kristoffer Vitting-Seerup Yun Chen Mehmet Coskun Yuan Li Bobby Zhao Sheng Lo Pia Klausen Pawel Jan Schweiger Anders Gorm Pedersen Nicolas Rapin Kerstin Skovgaard Katja Dahlgaard Robin Andersson Thilde Bagger Terkelsen Berit Lilje Jesper Thorvald Troelsen Andreas Munk Petersen Kim Bak Jensen Ismail Gögenur Peter Thielsen Jakob Benedict Seidelin Ole Haagen Nielsen Jacob Tveiten Bjerrum Albin Sandelin
author_facet	Mette Boyd Malte Thodberg Morana Vitezic Jette Bornholdt Kristoffer Vitting-Seerup Yun Chen Mehmet Coskun Yuan Li Bobby Zhao Sheng Lo Pia Klausen Pawel Jan Schweiger Anders Gorm Pedersen Nicolas Rapin Kerstin Skovgaard Katja Dahlgaard Robin Andersson Thilde Bagger Terkelsen Berit Lilje Jesper Thorvald Troelsen Andreas Munk Petersen Kim Bak Jensen Ismail Gögenur Peter Thielsen Jakob Benedict Seidelin Ole Haagen Nielsen Jacob Tveiten Bjerrum Albin Sandelin
author_sort	Mette Boyd
title	Characterization of the enhancer and promoter landscape of inflammatory bowel disease from human colon biopsies
title_short	Characterization of the enhancer and promoter landscape of inflammatory bowel disease from human colon biopsies
title_full	Characterization of the enhancer and promoter landscape of inflammatory bowel disease from human colon biopsies
title_fullStr	Characterization of the enhancer and promoter landscape of inflammatory bowel disease from human colon biopsies
title_full_unstemmed	Characterization of the enhancer and promoter landscape of inflammatory bowel disease from human colon biopsies
title_sort	characterization of the enhancer and promoter landscape of inflammatory bowel disease from human colon biopsies
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/e32e0b001f3f40cfa76d4515cf61a036
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Characterization of the enhancer and promoter landscape of inflammatory bowel disease from human colon biopsies

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