Biological process activity transformation of single cell gene expression for cross-species alignment

Single cell RNA-Seq data can report on cellular types and states, but low signal-to noise and sparse data can make interpretation of cellular state difficult. Here the authors propose a transformation strategy to map RNA-Seq data to biological process activities that are species-agnostic and allow f...

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Bibliographic Details
Main Authors: Hongxu Ding, Andrew Blair, Ying Yang, Joshua M. Stuart
Format: article
Language:EN
Published: Nature Portfolio 2019
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Online Access:https://doaj.org/article/e32e60d474f14311b3573e25cb1cad5f
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