Single cell transcriptomics of human epidermis identifies basal stem cell transition states

The mechanisms regulating stem cells to give rise to human interfollicular epidermis are unclear. Here, the authors use single cell RNA sequencing to identify heterogeneity within the human neonatal interfollicular epidermis and distinct spatial positioning of at least four basal stem cell populatio...

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Autores principales: Shuxiong Wang, Michael L. Drummond, Christian F. Guerrero-Juarez, Eric Tarapore, Adam L. MacLean, Adam R. Stabell, Stephanie C. Wu, Guadalupe Gutierrez, Bao T. That, Claudia A. Benavente, Qing Nie, Scott X. Atwood
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Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/e3323cb879d1430da063e81e74e2181d
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spelling oai:doaj.org-article:e3323cb879d1430da063e81e74e2181d2021-12-02T18:53:15ZSingle cell transcriptomics of human epidermis identifies basal stem cell transition states10.1038/s41467-020-18075-72041-1723https://doaj.org/article/e3323cb879d1430da063e81e74e2181d2020-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-18075-7https://doaj.org/toc/2041-1723The mechanisms regulating stem cells to give rise to human interfollicular epidermis are unclear. Here, the authors use single cell RNA sequencing to identify heterogeneity within the human neonatal interfollicular epidermis and distinct spatial positioning of at least four basal stem cell populations.Shuxiong WangMichael L. DrummondChristian F. Guerrero-JuarezEric TaraporeAdam L. MacLeanAdam R. StabellStephanie C. WuGuadalupe GutierrezBao T. ThatClaudia A. BenaventeQing NieScott X. AtwoodNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Shuxiong Wang
Michael L. Drummond
Christian F. Guerrero-Juarez
Eric Tarapore
Adam L. MacLean
Adam R. Stabell
Stephanie C. Wu
Guadalupe Gutierrez
Bao T. That
Claudia A. Benavente
Qing Nie
Scott X. Atwood
Single cell transcriptomics of human epidermis identifies basal stem cell transition states
description The mechanisms regulating stem cells to give rise to human interfollicular epidermis are unclear. Here, the authors use single cell RNA sequencing to identify heterogeneity within the human neonatal interfollicular epidermis and distinct spatial positioning of at least four basal stem cell populations.
format article
author Shuxiong Wang
Michael L. Drummond
Christian F. Guerrero-Juarez
Eric Tarapore
Adam L. MacLean
Adam R. Stabell
Stephanie C. Wu
Guadalupe Gutierrez
Bao T. That
Claudia A. Benavente
Qing Nie
Scott X. Atwood
author_facet Shuxiong Wang
Michael L. Drummond
Christian F. Guerrero-Juarez
Eric Tarapore
Adam L. MacLean
Adam R. Stabell
Stephanie C. Wu
Guadalupe Gutierrez
Bao T. That
Claudia A. Benavente
Qing Nie
Scott X. Atwood
author_sort Shuxiong Wang
title Single cell transcriptomics of human epidermis identifies basal stem cell transition states
title_short Single cell transcriptomics of human epidermis identifies basal stem cell transition states
title_full Single cell transcriptomics of human epidermis identifies basal stem cell transition states
title_fullStr Single cell transcriptomics of human epidermis identifies basal stem cell transition states
title_full_unstemmed Single cell transcriptomics of human epidermis identifies basal stem cell transition states
title_sort single cell transcriptomics of human epidermis identifies basal stem cell transition states
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/e3323cb879d1430da063e81e74e2181d
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