Single cell transcriptomics of human epidermis identifies basal stem cell transition states
The mechanisms regulating stem cells to give rise to human interfollicular epidermis are unclear. Here, the authors use single cell RNA sequencing to identify heterogeneity within the human neonatal interfollicular epidermis and distinct spatial positioning of at least four basal stem cell populatio...
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Nature Portfolio
2020
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oai:doaj.org-article:e3323cb879d1430da063e81e74e2181d2021-12-02T18:53:15ZSingle cell transcriptomics of human epidermis identifies basal stem cell transition states10.1038/s41467-020-18075-72041-1723https://doaj.org/article/e3323cb879d1430da063e81e74e2181d2020-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-18075-7https://doaj.org/toc/2041-1723The mechanisms regulating stem cells to give rise to human interfollicular epidermis are unclear. Here, the authors use single cell RNA sequencing to identify heterogeneity within the human neonatal interfollicular epidermis and distinct spatial positioning of at least four basal stem cell populations.Shuxiong WangMichael L. DrummondChristian F. Guerrero-JuarezEric TaraporeAdam L. MacLeanAdam R. StabellStephanie C. WuGuadalupe GutierrezBao T. ThatClaudia A. BenaventeQing NieScott X. AtwoodNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-14 (2020) |
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DOAJ |
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EN |
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Science Q |
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Science Q Shuxiong Wang Michael L. Drummond Christian F. Guerrero-Juarez Eric Tarapore Adam L. MacLean Adam R. Stabell Stephanie C. Wu Guadalupe Gutierrez Bao T. That Claudia A. Benavente Qing Nie Scott X. Atwood Single cell transcriptomics of human epidermis identifies basal stem cell transition states |
description |
The mechanisms regulating stem cells to give rise to human interfollicular epidermis are unclear. Here, the authors use single cell RNA sequencing to identify heterogeneity within the human neonatal interfollicular epidermis and distinct spatial positioning of at least four basal stem cell populations. |
format |
article |
author |
Shuxiong Wang Michael L. Drummond Christian F. Guerrero-Juarez Eric Tarapore Adam L. MacLean Adam R. Stabell Stephanie C. Wu Guadalupe Gutierrez Bao T. That Claudia A. Benavente Qing Nie Scott X. Atwood |
author_facet |
Shuxiong Wang Michael L. Drummond Christian F. Guerrero-Juarez Eric Tarapore Adam L. MacLean Adam R. Stabell Stephanie C. Wu Guadalupe Gutierrez Bao T. That Claudia A. Benavente Qing Nie Scott X. Atwood |
author_sort |
Shuxiong Wang |
title |
Single cell transcriptomics of human epidermis identifies basal stem cell transition states |
title_short |
Single cell transcriptomics of human epidermis identifies basal stem cell transition states |
title_full |
Single cell transcriptomics of human epidermis identifies basal stem cell transition states |
title_fullStr |
Single cell transcriptomics of human epidermis identifies basal stem cell transition states |
title_full_unstemmed |
Single cell transcriptomics of human epidermis identifies basal stem cell transition states |
title_sort |
single cell transcriptomics of human epidermis identifies basal stem cell transition states |
publisher |
Nature Portfolio |
publishDate |
2020 |
url |
https://doaj.org/article/e3323cb879d1430da063e81e74e2181d |
work_keys_str_mv |
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