Exploring Approaches for Detecting Protein Functional Similarity within an Orthology-based Framework
Abstract Protein functional similarity based on gene ontology (GO) annotations serves as a powerful tool when comparing proteins on a functional level in applications such as protein-protein interaction prediction, gene prioritization, and disease gene discovery. Functional similarity (FS) is usuall...
Guardado en:
Autores principales: | Christian X. Weichenberger, Antonia Palermo, Peter P. Pramstaller, Francisco S. Domingues |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2017
|
Materias: | |
Acceso en línea: | https://doaj.org/article/e3349d65cd56497ba631cc5306b0a9e7 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Resolving the ortholog conjecture: orthologs tend to be weakly, but significantly, more similar in function than paralogs.
por: Adrian M Altenhoff, et al.
Publicado: (2012) -
On the Use of Gene Ontology Annotations to Assess Functional Similarity among Orthologs and Paralogs: A Short Report.
por: Paul D Thomas, et al.
Publicado: (2012) -
Total Ortholog Median Matrix as an alternative unsupervised approach for phylogenomics based on evolutionary distance between protein coding genes
por: Sandra Regina Maruyama, et al.
Publicado: (2021) -
Inferring hierarchical orthologous groups from orthologous gene pairs.
por: Adrian M Altenhoff, et al.
Publicado: (2013) -
Getting started in gene orthology and functional analysis.
por: Gang Fang, et al.
Publicado: (2010)