Exploring Approaches for Detecting Protein Functional Similarity within an Orthology-based Framework

Abstract Protein functional similarity based on gene ontology (GO) annotations serves as a powerful tool when comparing proteins on a functional level in applications such as protein-protein interaction prediction, gene prioritization, and disease gene discovery. Functional similarity (FS) is usuall...

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Autores principales: Christian X. Weichenberger, Antonia Palermo, Peter P. Pramstaller, Francisco S. Domingues
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/e3349d65cd56497ba631cc5306b0a9e7
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