Prefrontal parvalbumin interneurons require juvenile social experience to establish adult social behavior

Isolation during critical periods of development prevents development of normal social behaviours in mice, and this is thought to involve the prefrontal cortex. Here, the authors identify an activation pattern in parvalbumin-positive interneurons in the dorsal medial prefrontal cortex that when acti...

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Autores principales:	Lucy K. Bicks, Kazuhiko Yamamuro, Meghan E. Flanigan, Julia Minjung Kim, Daisuke Kato, Elizabeth K. Lucas, Hiroyuki Koike, Michelle S. Peng, Daniel M. Brady, Sandhya Chandrasekaran, Kevin J. Norman, Milo R. Smith, Roger L. Clem, Scott J. Russo, Schahram Akbarian, Hirofumi Morishita
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/e3415caf868e48819828d52e7b559a2f
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spelling	oai:doaj.org-article:e3415caf868e48819828d52e7b559a2f2021-12-02T15:39:07ZPrefrontal parvalbumin interneurons require juvenile social experience to establish adult social behavior10.1038/s41467-020-14740-z2041-1723https://doaj.org/article/e3415caf868e48819828d52e7b559a2f2020-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-14740-zhttps://doaj.org/toc/2041-1723Isolation during critical periods of development prevents development of normal social behaviours in mice, and this is thought to involve the prefrontal cortex. Here, the authors identify an activation pattern in parvalbumin-positive interneurons in the dorsal medial prefrontal cortex that when activated promotes sociability behaviours in mice.Lucy K. BicksKazuhiko YamamuroMeghan E. FlaniganJulia Minjung KimDaisuke KatoElizabeth K. LucasHiroyuki KoikeMichelle S. PengDaniel M. BradySandhya ChandrasekaranKevin J. NormanMilo R. SmithRoger L. ClemScott J. RussoSchahram AkbarianHirofumi MorishitaNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Lucy K. Bicks Kazuhiko Yamamuro Meghan E. Flanigan Julia Minjung Kim Daisuke Kato Elizabeth K. Lucas Hiroyuki Koike Michelle S. Peng Daniel M. Brady Sandhya Chandrasekaran Kevin J. Norman Milo R. Smith Roger L. Clem Scott J. Russo Schahram Akbarian Hirofumi Morishita Prefrontal parvalbumin interneurons require juvenile social experience to establish adult social behavior
description	Isolation during critical periods of development prevents development of normal social behaviours in mice, and this is thought to involve the prefrontal cortex. Here, the authors identify an activation pattern in parvalbumin-positive interneurons in the dorsal medial prefrontal cortex that when activated promotes sociability behaviours in mice.
format	article
author	Lucy K. Bicks Kazuhiko Yamamuro Meghan E. Flanigan Julia Minjung Kim Daisuke Kato Elizabeth K. Lucas Hiroyuki Koike Michelle S. Peng Daniel M. Brady Sandhya Chandrasekaran Kevin J. Norman Milo R. Smith Roger L. Clem Scott J. Russo Schahram Akbarian Hirofumi Morishita
author_facet	Lucy K. Bicks Kazuhiko Yamamuro Meghan E. Flanigan Julia Minjung Kim Daisuke Kato Elizabeth K. Lucas Hiroyuki Koike Michelle S. Peng Daniel M. Brady Sandhya Chandrasekaran Kevin J. Norman Milo R. Smith Roger L. Clem Scott J. Russo Schahram Akbarian Hirofumi Morishita
author_sort	Lucy K. Bicks
title	Prefrontal parvalbumin interneurons require juvenile social experience to establish adult social behavior
title_short	Prefrontal parvalbumin interneurons require juvenile social experience to establish adult social behavior
title_full	Prefrontal parvalbumin interneurons require juvenile social experience to establish adult social behavior
title_fullStr	Prefrontal parvalbumin interneurons require juvenile social experience to establish adult social behavior
title_full_unstemmed	Prefrontal parvalbumin interneurons require juvenile social experience to establish adult social behavior
title_sort	prefrontal parvalbumin interneurons require juvenile social experience to establish adult social behavior
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/e3415caf868e48819828d52e7b559a2f
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Prefrontal parvalbumin interneurons require juvenile social experience to establish adult social behavior

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