Nicotinamide riboside is uniquely and orally bioavailable in mice and humans

NAD+ is an important coenzyme that mediates cellular metabolism and defends against stresses due to age and overnutrition. Here the authors demonstrate unique bioavailability of the NAD+ precursor vitamin nicotinamide riboside (NR) in mice and humans, and show that NR safely elevates human NAD+.

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Autores principales:	Samuel A. J. Trammell, Mark S. Schmidt, Benjamin J. Weidemann, Philip Redpath, Frank Jaksch, Ryan W. Dellinger, Zhonggang Li, E. Dale Abel, Marie E. Migaud, Charles Brenner
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/e34c321832984f148c714a8f86a0f42b
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spelling	oai:doaj.org-article:e34c321832984f148c714a8f86a0f42b2021-12-02T14:38:57ZNicotinamide riboside is uniquely and orally bioavailable in mice and humans10.1038/ncomms129482041-1723https://doaj.org/article/e34c321832984f148c714a8f86a0f42b2016-10-01T00:00:00Zhttps://doi.org/10.1038/ncomms12948https://doaj.org/toc/2041-1723NAD+ is an important coenzyme that mediates cellular metabolism and defends against stresses due to age and overnutrition. Here the authors demonstrate unique bioavailability of the NAD+ precursor vitamin nicotinamide riboside (NR) in mice and humans, and show that NR safely elevates human NAD+.Samuel A. J. TrammellMark S. SchmidtBenjamin J. WeidemannPhilip RedpathFrank JakschRyan W. DellingerZhonggang LiE. Dale AbelMarie E. MigaudCharles BrennerNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-14 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Samuel A. J. Trammell Mark S. Schmidt Benjamin J. Weidemann Philip Redpath Frank Jaksch Ryan W. Dellinger Zhonggang Li E. Dale Abel Marie E. Migaud Charles Brenner Nicotinamide riboside is uniquely and orally bioavailable in mice and humans
description	NAD+ is an important coenzyme that mediates cellular metabolism and defends against stresses due to age and overnutrition. Here the authors demonstrate unique bioavailability of the NAD+ precursor vitamin nicotinamide riboside (NR) in mice and humans, and show that NR safely elevates human NAD+.
format	article
author	Samuel A. J. Trammell Mark S. Schmidt Benjamin J. Weidemann Philip Redpath Frank Jaksch Ryan W. Dellinger Zhonggang Li E. Dale Abel Marie E. Migaud Charles Brenner
author_facet	Samuel A. J. Trammell Mark S. Schmidt Benjamin J. Weidemann Philip Redpath Frank Jaksch Ryan W. Dellinger Zhonggang Li E. Dale Abel Marie E. Migaud Charles Brenner
author_sort	Samuel A. J. Trammell
title	Nicotinamide riboside is uniquely and orally bioavailable in mice and humans
title_short	Nicotinamide riboside is uniquely and orally bioavailable in mice and humans
title_full	Nicotinamide riboside is uniquely and orally bioavailable in mice and humans
title_fullStr	Nicotinamide riboside is uniquely and orally bioavailable in mice and humans
title_full_unstemmed	Nicotinamide riboside is uniquely and orally bioavailable in mice and humans
title_sort	nicotinamide riboside is uniquely and orally bioavailable in mice and humans
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/e34c321832984f148c714a8f86a0f42b
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Nicotinamide riboside is uniquely and orally bioavailable in mice and humans

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