Telomeres reforged with non-telomeric sequences in mouse embryonic stem cells
Telomeres can be maintained by a telomerase-independent mechanism called an alternative lengthening of telomeres (ALT). Here the authors use mouse Terc (telomerase RNA) knockout embryonic cells and provide longitudinal analysis of ALT telomeres maintained with non-telomeric sequences.
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Nature Portfolio
2021
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oai:doaj.org-article:e34d9693dd474032a8c9e6b879a34f7d2021-12-02T14:21:24ZTelomeres reforged with non-telomeric sequences in mouse embryonic stem cells10.1038/s41467-021-21341-x2041-1723https://doaj.org/article/e34d9693dd474032a8c9e6b879a34f7d2021-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-21341-xhttps://doaj.org/toc/2041-1723Telomeres can be maintained by a telomerase-independent mechanism called an alternative lengthening of telomeres (ALT). Here the authors use mouse Terc (telomerase RNA) knockout embryonic cells and provide longitudinal analysis of ALT telomeres maintained with non-telomeric sequences.Chuna KimSanghyun SungJong-Seo KimHyunji LeeYoonseok JungSanghee ShinEunkyeong KimJenny J. SeoJun KimDaeun KimHiroyuki NiidaV. Narry KimDaechan ParkJunho LeeNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-15 (2021) |
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EN |
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Science Q Chuna Kim Sanghyun Sung Jong-Seo Kim Hyunji Lee Yoonseok Jung Sanghee Shin Eunkyeong Kim Jenny J. Seo Jun Kim Daeun Kim Hiroyuki Niida V. Narry Kim Daechan Park Junho Lee Telomeres reforged with non-telomeric sequences in mouse embryonic stem cells |
description |
Telomeres can be maintained by a telomerase-independent mechanism called an alternative lengthening of telomeres (ALT). Here the authors use mouse Terc (telomerase RNA) knockout embryonic cells and provide longitudinal analysis of ALT telomeres maintained with non-telomeric sequences. |
format |
article |
author |
Chuna Kim Sanghyun Sung Jong-Seo Kim Hyunji Lee Yoonseok Jung Sanghee Shin Eunkyeong Kim Jenny J. Seo Jun Kim Daeun Kim Hiroyuki Niida V. Narry Kim Daechan Park Junho Lee |
author_facet |
Chuna Kim Sanghyun Sung Jong-Seo Kim Hyunji Lee Yoonseok Jung Sanghee Shin Eunkyeong Kim Jenny J. Seo Jun Kim Daeun Kim Hiroyuki Niida V. Narry Kim Daechan Park Junho Lee |
author_sort |
Chuna Kim |
title |
Telomeres reforged with non-telomeric sequences in mouse embryonic stem cells |
title_short |
Telomeres reforged with non-telomeric sequences in mouse embryonic stem cells |
title_full |
Telomeres reforged with non-telomeric sequences in mouse embryonic stem cells |
title_fullStr |
Telomeres reforged with non-telomeric sequences in mouse embryonic stem cells |
title_full_unstemmed |
Telomeres reforged with non-telomeric sequences in mouse embryonic stem cells |
title_sort |
telomeres reforged with non-telomeric sequences in mouse embryonic stem cells |
publisher |
Nature Portfolio |
publishDate |
2021 |
url |
https://doaj.org/article/e34d9693dd474032a8c9e6b879a34f7d |
work_keys_str_mv |
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1718391578557415424 |