Telomeres reforged with non-telomeric sequences in mouse embryonic stem cells

Telomeres can be maintained by a telomerase-independent mechanism called an alternative lengthening of telomeres (ALT). Here the authors use mouse Terc (telomerase RNA) knockout embryonic cells and provide longitudinal analysis of ALT telomeres maintained with non-telomeric sequences.

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Autores principales: Chuna Kim, Sanghyun Sung, Jong-Seo Kim, Hyunji Lee, Yoonseok Jung, Sanghee Shin, Eunkyeong Kim, Jenny J. Seo, Jun Kim, Daeun Kim, Hiroyuki Niida, V. Narry Kim, Daechan Park, Junho Lee
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Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/e34d9693dd474032a8c9e6b879a34f7d
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spelling oai:doaj.org-article:e34d9693dd474032a8c9e6b879a34f7d2021-12-02T14:21:24ZTelomeres reforged with non-telomeric sequences in mouse embryonic stem cells10.1038/s41467-021-21341-x2041-1723https://doaj.org/article/e34d9693dd474032a8c9e6b879a34f7d2021-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-21341-xhttps://doaj.org/toc/2041-1723Telomeres can be maintained by a telomerase-independent mechanism called an alternative lengthening of telomeres (ALT). Here the authors use mouse Terc (telomerase RNA) knockout embryonic cells and provide longitudinal analysis of ALT telomeres maintained with non-telomeric sequences.Chuna KimSanghyun SungJong-Seo KimHyunji LeeYoonseok JungSanghee ShinEunkyeong KimJenny J. SeoJun KimDaeun KimHiroyuki NiidaV. Narry KimDaechan ParkJunho LeeNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Chuna Kim
Sanghyun Sung
Jong-Seo Kim
Hyunji Lee
Yoonseok Jung
Sanghee Shin
Eunkyeong Kim
Jenny J. Seo
Jun Kim
Daeun Kim
Hiroyuki Niida
V. Narry Kim
Daechan Park
Junho Lee
Telomeres reforged with non-telomeric sequences in mouse embryonic stem cells
description Telomeres can be maintained by a telomerase-independent mechanism called an alternative lengthening of telomeres (ALT). Here the authors use mouse Terc (telomerase RNA) knockout embryonic cells and provide longitudinal analysis of ALT telomeres maintained with non-telomeric sequences.
format article
author Chuna Kim
Sanghyun Sung
Jong-Seo Kim
Hyunji Lee
Yoonseok Jung
Sanghee Shin
Eunkyeong Kim
Jenny J. Seo
Jun Kim
Daeun Kim
Hiroyuki Niida
V. Narry Kim
Daechan Park
Junho Lee
author_facet Chuna Kim
Sanghyun Sung
Jong-Seo Kim
Hyunji Lee
Yoonseok Jung
Sanghee Shin
Eunkyeong Kim
Jenny J. Seo
Jun Kim
Daeun Kim
Hiroyuki Niida
V. Narry Kim
Daechan Park
Junho Lee
author_sort Chuna Kim
title Telomeres reforged with non-telomeric sequences in mouse embryonic stem cells
title_short Telomeres reforged with non-telomeric sequences in mouse embryonic stem cells
title_full Telomeres reforged with non-telomeric sequences in mouse embryonic stem cells
title_fullStr Telomeres reforged with non-telomeric sequences in mouse embryonic stem cells
title_full_unstemmed Telomeres reforged with non-telomeric sequences in mouse embryonic stem cells
title_sort telomeres reforged with non-telomeric sequences in mouse embryonic stem cells
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/e34d9693dd474032a8c9e6b879a34f7d
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