Advances in patient-controlled analgesia: the role of fentanyl ITS

Ian Power, Jon G McCormackDepartment of Anaesthesia, Critical Care and Pain Medicine, The University of Edinburgh, Royal Infirmary, Edinburgh, UKAbstract: Effective pain relief is an essential component of a patient&rsquo;s peri-operative care package. Good analgesia has been shown to reduce...

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Autores principales:	Ian Power, Jon G McCormack
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2009
Materias:	Medical technology R855-855.5
Acceso en línea:	https://doaj.org/article/e3559456fc674900989ee34aa3ba387f
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spelling	oai:doaj.org-article:e3559456fc674900989ee34aa3ba387f2021-12-02T02:06:44ZAdvances in patient-controlled analgesia: the role of fentanyl ITS1179-1470https://doaj.org/article/e3559456fc674900989ee34aa3ba387f2009-01-01T00:00:00Zhttp://www.dovepress.com/advances-in-patient-controlled-analgesia-the-role-of-fentanyl-its-a2785https://doaj.org/toc/1179-1470Ian Power, Jon G McCormackDepartment of Anaesthesia, Critical Care and Pain Medicine, The University of Edinburgh, Royal Infirmary, Edinburgh, UKAbstract: Effective pain relief is an essential component of a patient&rsquo;s peri-operative care package. Good analgesia has been shown to reduce the incidence of cardiovascular, respiratory and thrombo-embolic complications following surgery. Satisfactory analgesia facilitates early patient ambulation following surgery, which may reduce in-patient stay. Patient-controlled analgesia (PCA) systems are a well established standard therapy for acute post-operative pain; however some practical limitations limit their clinical utility. The fentanyl inotophoretic transdermal system (ITS) is a novel self-contained needle-free PCA device, which delivers boluses of fentanyl transdermally. This system has been shown to provide analgesia equivalent to conventional PCA modalities, with unique design features that may confer advantages to patients and staff, including facilitating patient mobilization in the post-operative phase. This review will discuss the technology of iontophoretic systems, the pharmacology of transdermal fentanyl delivery, and some practical implications of the fentanyl ITS.Keywords: iontophoresis, transdermal, patient-controlled analgesia, fentanyl, post-operative pain Ian PowerJon G McCormackDove Medical PressarticleMedical technologyR855-855.5ENMedical Devices: Evidence and Research, Vol 2008, Iss default, Pp 49-57 (2009)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medical technology R855-855.5
spellingShingle	Medical technology R855-855.5 Ian Power Jon G McCormack Advances in patient-controlled analgesia: the role of fentanyl ITS
description	Ian Power, Jon G McCormackDepartment of Anaesthesia, Critical Care and Pain Medicine, The University of Edinburgh, Royal Infirmary, Edinburgh, UKAbstract: Effective pain relief is an essential component of a patient&rsquo;s peri-operative care package. Good analgesia has been shown to reduce the incidence of cardiovascular, respiratory and thrombo-embolic complications following surgery. Satisfactory analgesia facilitates early patient ambulation following surgery, which may reduce in-patient stay. Patient-controlled analgesia (PCA) systems are a well established standard therapy for acute post-operative pain; however some practical limitations limit their clinical utility. The fentanyl inotophoretic transdermal system (ITS) is a novel self-contained needle-free PCA device, which delivers boluses of fentanyl transdermally. This system has been shown to provide analgesia equivalent to conventional PCA modalities, with unique design features that may confer advantages to patients and staff, including facilitating patient mobilization in the post-operative phase. This review will discuss the technology of iontophoretic systems, the pharmacology of transdermal fentanyl delivery, and some practical implications of the fentanyl ITS.Keywords: iontophoresis, transdermal, patient-controlled analgesia, fentanyl, post-operative pain
format	article
author	Ian Power Jon G McCormack
author_facet	Ian Power Jon G McCormack
author_sort	Ian Power
title	Advances in patient-controlled analgesia: the role of fentanyl ITS
title_short	Advances in patient-controlled analgesia: the role of fentanyl ITS
title_full	Advances in patient-controlled analgesia: the role of fentanyl ITS
title_fullStr	Advances in patient-controlled analgesia: the role of fentanyl ITS
title_full_unstemmed	Advances in patient-controlled analgesia: the role of fentanyl ITS
title_sort	advances in patient-controlled analgesia: the role of fentanyl its
publisher	Dove Medical Press
publishDate	2009
url	https://doaj.org/article/e3559456fc674900989ee34aa3ba387f
work_keys_str_mv	AT ianpower advancesinpatientcontrolledanalgesiatheroleoffentanylits AT jongmccormack advancesinpatientcontrolledanalgesiatheroleoffentanylits
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Advances in patient-controlled analgesia: the role of fentanyl ITS

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