IL-27 Negatively Regulates Tip-DC Development during Infection

TNF/iNOS-producing dendritic cells (Tip-DCs) are at the front line as immune effector cells to fight off a broad range of invading microbes. Excessive development of Tip-DCs contributes to tissue destruction.

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Detalles Bibliográficos
Autores principales: Gongguan Liu, Osama Abas, Yong Fu, Yanli Chen, Ashley B. Strickland, Donglei Sun, Meiqing Shi
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2021
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Acceso en línea:https://doaj.org/article/e3567fc2977c4bc7affcd6829ff830d0
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Descripción
Sumario:TNF/iNOS-producing dendritic cells (Tip-DCs) are at the front line as immune effector cells to fight off a broad range of invading microbes. Excessive development of Tip-DCs contributes to tissue destruction.