Differential expression profile of gluten-specific T cells identified by single-cell RNA-seq.
Gluten-specific CD4+ T cells drive the pathogenesis of celiac disease and circulating gluten-specific T cells can be identified by staining with HLA-DQ:gluten tetramers. In this first single-cell RNA-seq study of tetramer-sorted T cells from untreated celiac disease patients blood, we found that glu...
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Autores principales: | Ying Yao, Łukasz Wyrozżemski, Knut E A Lundin, Geir Kjetil Sandve, Shuo-Wang Qiao |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/e35c933146b7496389afe831b83ade44 |
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