Alterations in β-Cell Sphingolipid Profile Associated with ER Stress and iPLA<sub>2</sub>β: Another Contributor to β-Cell Apoptosis in Type 1 Diabetes
Type 1 diabetes (T1D) development, in part, is due to ER stress-induced β-cell apoptosis. Activation of the Ca<sup>2+</sup>-independent phospholipase A<sub>2</sub> beta (iPLA<sub>2</sub>β) leads to the generation of pro-inflammatory eicosanoids, which contribute t...
Guardado en:
| Autores principales: | , , , , , |
|---|---|
| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
MDPI AG
2021
|
| Materias: | |
| Acceso en línea: | https://doaj.org/article/e36a69fd56814486a980de5987a4cd9a |
| Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Sea el primero en dejar un comentario!