A global lipid map defines a network essential for Zika virus replication

Zika virus (ZIKV) remodels intracellular membranes for replication, but the role of different lipid types for infection and disease is unclear. Here, the authors perform lipidomics, show perturbation of the lipid network during ZIKV infection and show that ceramides are important for ZIKV infection.

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Autores principales:	Hans C. Leier, Jules B. Weinstein, Jennifer E. Kyle, Joon-Yong Lee, Lisa M. Bramer, Kelly G. Stratton, Douglas Kempthorne, Aaron R. Navratil, Endale G. Tafesse, Thorsten Hornemann, William B. Messer, Edward A. Dennis, Thomas O. Metz, Eric Barklis, Fikadu G. Tafesse
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/e3700eeb09074ab692ee327211963128
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spelling	oai:doaj.org-article:e3700eeb09074ab692ee3272119631282021-12-02T16:43:46ZA global lipid map defines a network essential for Zika virus replication10.1038/s41467-020-17433-92041-1723https://doaj.org/article/e3700eeb09074ab692ee3272119631282020-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-17433-9https://doaj.org/toc/2041-1723Zika virus (ZIKV) remodels intracellular membranes for replication, but the role of different lipid types for infection and disease is unclear. Here, the authors perform lipidomics, show perturbation of the lipid network during ZIKV infection and show that ceramides are important for ZIKV infection.Hans C. LeierJules B. WeinsteinJennifer E. KyleJoon-Yong LeeLisa M. BramerKelly G. StrattonDouglas KempthorneAaron R. NavratilEndale G. TafesseThorsten HornemannWilliam B. MesserEdward A. DennisThomas O. MetzEric BarklisFikadu G. TafesseNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Hans C. Leier Jules B. Weinstein Jennifer E. Kyle Joon-Yong Lee Lisa M. Bramer Kelly G. Stratton Douglas Kempthorne Aaron R. Navratil Endale G. Tafesse Thorsten Hornemann William B. Messer Edward A. Dennis Thomas O. Metz Eric Barklis Fikadu G. Tafesse A global lipid map defines a network essential for Zika virus replication
description	Zika virus (ZIKV) remodels intracellular membranes for replication, but the role of different lipid types for infection and disease is unclear. Here, the authors perform lipidomics, show perturbation of the lipid network during ZIKV infection and show that ceramides are important for ZIKV infection.
format	article
author	Hans C. Leier Jules B. Weinstein Jennifer E. Kyle Joon-Yong Lee Lisa M. Bramer Kelly G. Stratton Douglas Kempthorne Aaron R. Navratil Endale G. Tafesse Thorsten Hornemann William B. Messer Edward A. Dennis Thomas O. Metz Eric Barklis Fikadu G. Tafesse
author_facet	Hans C. Leier Jules B. Weinstein Jennifer E. Kyle Joon-Yong Lee Lisa M. Bramer Kelly G. Stratton Douglas Kempthorne Aaron R. Navratil Endale G. Tafesse Thorsten Hornemann William B. Messer Edward A. Dennis Thomas O. Metz Eric Barklis Fikadu G. Tafesse
author_sort	Hans C. Leier
title	A global lipid map defines a network essential for Zika virus replication
title_short	A global lipid map defines a network essential for Zika virus replication
title_full	A global lipid map defines a network essential for Zika virus replication
title_fullStr	A global lipid map defines a network essential for Zika virus replication
title_full_unstemmed	A global lipid map defines a network essential for Zika virus replication
title_sort	global lipid map defines a network essential for zika virus replication
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/e3700eeb09074ab692ee327211963128
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A global lipid map defines a network essential for Zika virus replication

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