Femtogram Level Sensitivity achieved by Surface Engineered Silica Nanoparticles in the Early Detection of HIV Infection

Abstract We have engineered streptavidin labelled Europium doped fluorescent silica nanoparticles which significantly increased sensitivity without compromising the specificity of the immunoassay. As a proof of concept, a time resolved fluorescence based sandwich immunoassay was developed to detect...

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Autores principales: L. A. Avinash Chunduri, Aditya Kurdekar, Mohan Kumar Haleyurgirisetty, Eswarappa Pradeep Bulagonda, Venkataramaniah Kamisetti, Indira K. Hewlett
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/e37182fe488446fea83b8870b4373791
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