Exosomes maintain cellular homeostasis by excreting harmful DNA from cells

The role of exosomes in intercellular communication is well established, however less in known about the biological roles of exosome secretion in exosome-secreting cells. Here the authors show that exosome secretion controls cellular homeostasis in exosome-secreting cells by removing harmful cytopla...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Akiko Takahashi, Ryo Okada, Koji Nagao, Yuka Kawamata, Aki Hanyu, Shin Yoshimoto, Masaki Takasugi, Sugiko Watanabe, Masato T Kanemaki, Chikashi Obuse, Eiji Hara
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/e3766fd98b5947d28ef1846c81904cc6
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:e3766fd98b5947d28ef1846c81904cc6
record_format	dspace
spelling	oai:doaj.org-article:e3766fd98b5947d28ef1846c81904cc62021-12-02T17:01:23ZExosomes maintain cellular homeostasis by excreting harmful DNA from cells10.1038/ncomms152872041-1723https://doaj.org/article/e3766fd98b5947d28ef1846c81904cc62017-05-01T00:00:00Zhttps://doi.org/10.1038/ncomms15287https://doaj.org/toc/2041-1723The role of exosomes in intercellular communication is well established, however less in known about the biological roles of exosome secretion in exosome-secreting cells. Here the authors show that exosome secretion controls cellular homeostasis in exosome-secreting cells by removing harmful cytoplasmic DNA from cells.Akiko TakahashiRyo OkadaKoji NagaoYuka KawamataAki HanyuShin YoshimotoMasaki TakasugiSugiko WatanabeMasato T KanemakiChikashi ObuseEiji HaraNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-16 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Akiko Takahashi Ryo Okada Koji Nagao Yuka Kawamata Aki Hanyu Shin Yoshimoto Masaki Takasugi Sugiko Watanabe Masato T Kanemaki Chikashi Obuse Eiji Hara Exosomes maintain cellular homeostasis by excreting harmful DNA from cells
description	The role of exosomes in intercellular communication is well established, however less in known about the biological roles of exosome secretion in exosome-secreting cells. Here the authors show that exosome secretion controls cellular homeostasis in exosome-secreting cells by removing harmful cytoplasmic DNA from cells.
format	article
author	Akiko Takahashi Ryo Okada Koji Nagao Yuka Kawamata Aki Hanyu Shin Yoshimoto Masaki Takasugi Sugiko Watanabe Masato T Kanemaki Chikashi Obuse Eiji Hara
author_facet	Akiko Takahashi Ryo Okada Koji Nagao Yuka Kawamata Aki Hanyu Shin Yoshimoto Masaki Takasugi Sugiko Watanabe Masato T Kanemaki Chikashi Obuse Eiji Hara
author_sort	Akiko Takahashi
title	Exosomes maintain cellular homeostasis by excreting harmful DNA from cells
title_short	Exosomes maintain cellular homeostasis by excreting harmful DNA from cells
title_full	Exosomes maintain cellular homeostasis by excreting harmful DNA from cells
title_fullStr	Exosomes maintain cellular homeostasis by excreting harmful DNA from cells
title_full_unstemmed	Exosomes maintain cellular homeostasis by excreting harmful DNA from cells
title_sort	exosomes maintain cellular homeostasis by excreting harmful dna from cells
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/e3766fd98b5947d28ef1846c81904cc6
work_keys_str_mv	AT akikotakahashi exosomesmaintaincellularhomeostasisbyexcretingharmfuldnafromcells AT ryookada exosomesmaintaincellularhomeostasisbyexcretingharmfuldnafromcells AT kojinagao exosomesmaintaincellularhomeostasisbyexcretingharmfuldnafromcells AT yukakawamata exosomesmaintaincellularhomeostasisbyexcretingharmfuldnafromcells AT akihanyu exosomesmaintaincellularhomeostasisbyexcretingharmfuldnafromcells AT shinyoshimoto exosomesmaintaincellularhomeostasisbyexcretingharmfuldnafromcells AT masakitakasugi exosomesmaintaincellularhomeostasisbyexcretingharmfuldnafromcells AT sugikowatanabe exosomesmaintaincellularhomeostasisbyexcretingharmfuldnafromcells AT masatotkanemaki exosomesmaintaincellularhomeostasisbyexcretingharmfuldnafromcells AT chikashiobuse exosomesmaintaincellularhomeostasisbyexcretingharmfuldnafromcells AT eijihara exosomesmaintaincellularhomeostasisbyexcretingharmfuldnafromcells
_version_	1718382182684164096

Exosomes maintain cellular homeostasis by excreting harmful DNA from cells

Ejemplares similares