Fungal Inositol Pyrophosphate IP<sub>7</sub> Is Crucial for Metabolic Adaptation to the Host Environment and Pathogenicity
ABSTRACT Inositol pyrophosphates (PP-IPs) comprising inositol, phosphate, and pyrophosphate (PP) are essential for multiple functions in eukaryotes. Their role in fungal pathogens has never been addressed. Cryptococcus neoformans is a model pathogenic fungus causing life-threatening meningoencephali...
Guardado en:
Autores principales: | Sophie Lev, Cecilia Li, Desmarini Desmarini, Adolfo Saiardi, Nicole L. Fewings, Stephen D. Schibeci, Raghwa Sharma, Tania C. Sorrell, Julianne T. Djordjevic |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
American Society for Microbiology
2015
|
Materias: | |
Acceso en línea: | https://doaj.org/article/e381e61b8709482f8c838d7eaa4951f6 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
IP<sub>7</sub>-SPX Domain Interaction Controls Fungal Virulence by Stabilizing Phosphate Signaling Machinery
por: Desmarini Desmarini, et al.
Publicado: (2020) -
Identification of Aph1, a Phosphate-Regulated, Secreted, and Vacuolar Acid Phosphatase in <named-content content-type="genus-species">Cryptococcus neoformans</named-content>
por: Sophie Lev, et al.
Publicado: (2014) -
Pho4 Is Essential for Dissemination of <named-content content-type="genus-species">Cryptococcus neoformans</named-content> to the Host Brain by Promoting Phosphate Uptake and Growth at Alkaline pH
por: Sophie Lev, et al.
Publicado: (2017) -
Cardiac and Cerebellar Histomorphology and Inositol 1,4,5-Trisphosphate (IP<sub>3</sub>R) Perturbations in Adult <i>Xenopus laevis</i> Following Atrazine Exposure
por: Jaclyn Asouzu Johnson, et al.
Publicado: (2021) -
Human genome-wide RNAi screen identifies an essential role for inositol pyrophosphates in Type-I interferon response.
por: Niyas Kudukkil Pulloor, et al.
Publicado: (2014)