CYP51 Paralogue Structure Is Associated with Intrinsic Azole Resistance in Fungi

Azole antifungals are the main treatment for fungal disease in humans. Many species are intrinsically resistant to azoles—in other words all members of the species are resistant without prior exposure—and we do not understand why.

Guardado en:
Detalles Bibliográficos
Autores principales: N. Van Rhijn, M. Bromley, M. Richardson, P. Bowyer
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://doaj.org/article/e38bfc8e81a24a91802f24520d356506
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
Descripción
Sumario:Azole antifungals are the main treatment for fungal disease in humans. Many species are intrinsically resistant to azoles—in other words all members of the species are resistant without prior exposure—and we do not understand why.