CYP51 Paralogue Structure Is Associated with Intrinsic Azole Resistance in Fungi

Azole antifungals are the main treatment for fungal disease in humans. Many species are intrinsically resistant to azoles—in other words all members of the species are resistant without prior exposure—and we do not understand why.

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Autores principales:	N. Van Rhijn, M. Bromley, M. Richardson, P. Bowyer
Formato:	article
Lenguaje:	EN
Publicado:	American Society for Microbiology 2021
Materias:	Microbiology QR1-502
Acceso en línea:	https://doaj.org/article/e38bfc8e81a24a91802f24520d356506
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spelling	oai:doaj.org-article:e38bfc8e81a24a91802f24520d3565062021-11-03T21:52:36ZCYP51 Paralogue Structure Is Associated with Intrinsic Azole Resistance in Fungi2150-751110.1128/mBio.01945-21https://doaj.org/article/e38bfc8e81a24a91802f24520d3565062021-10-01T00:00:00Zhttps://journals.asm.org/doi/10.1128/mBio.01945-21https://doaj.org/toc/2150-7511 Azole antifungals are the main treatment for fungal disease in humans. Many species are intrinsically resistant to azoles—in other words all members of the species are resistant without prior exposure—and we do not understand why.N. Van RhijnM. BromleyM. RichardsonP. BowyerAmerican Society for MicrobiologyarticleMicrobiologyQR1-502ENmBio, Vol 12, Iss 5 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Microbiology QR1-502
spellingShingle	Microbiology QR1-502 N. Van Rhijn M. Bromley M. Richardson P. Bowyer CYP51 Paralogue Structure Is Associated with Intrinsic Azole Resistance in Fungi
description	Azole antifungals are the main treatment for fungal disease in humans. Many species are intrinsically resistant to azoles—in other words all members of the species are resistant without prior exposure—and we do not understand why.
format	article
author	N. Van Rhijn M. Bromley M. Richardson P. Bowyer
author_facet	N. Van Rhijn M. Bromley M. Richardson P. Bowyer
author_sort	N. Van Rhijn
title	CYP51 Paralogue Structure Is Associated with Intrinsic Azole Resistance in Fungi
title_short	CYP51 Paralogue Structure Is Associated with Intrinsic Azole Resistance in Fungi
title_full	CYP51 Paralogue Structure Is Associated with Intrinsic Azole Resistance in Fungi
title_fullStr	CYP51 Paralogue Structure Is Associated with Intrinsic Azole Resistance in Fungi
title_full_unstemmed	CYP51 Paralogue Structure Is Associated with Intrinsic Azole Resistance in Fungi
title_sort	cyp51 paralogue structure is associated with intrinsic azole resistance in fungi
publisher	American Society for Microbiology
publishDate	2021
url	https://doaj.org/article/e38bfc8e81a24a91802f24520d356506
work_keys_str_mv	AT nvanrhijn cyp51paraloguestructureisassociatedwithintrinsicazoleresistanceinfungi AT mbromley cyp51paraloguestructureisassociatedwithintrinsicazoleresistanceinfungi AT mrichardson cyp51paraloguestructureisassociatedwithintrinsicazoleresistanceinfungi AT pbowyer cyp51paraloguestructureisassociatedwithintrinsicazoleresistanceinfungi
_version_	1718445366046621696

CYP51 Paralogue Structure Is Associated with Intrinsic Azole Resistance in Fungi

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