Cholinergic neural activity directs retinal layer-specific angiogenesis and blood retinal barrier formation

During retinal development, waves of cholinergic neural activity play a role in retinal circuit development. Here, the authors show that this activity also contributes to layer-specific angiogenesis and formation of the blood-retinal barrier.

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Detalles Bibliográficos
Autores principales: G. A. Weiner, S. H. Shah, C. M. Angelopoulos, A. B. Bartakova, R. S. Pulido, A. Murphy, E. Nudleman, R. Daneman, J. L. Goldberg
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/e38c62e273a7445fa83a47558e76aed1
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Sumario:During retinal development, waves of cholinergic neural activity play a role in retinal circuit development. Here, the authors show that this activity also contributes to layer-specific angiogenesis and formation of the blood-retinal barrier.