Cholinergic neural activity directs retinal layer-specific angiogenesis and blood retinal barrier formation

During retinal development, waves of cholinergic neural activity play a role in retinal circuit development. Here, the authors show that this activity also contributes to layer-specific angiogenesis and formation of the blood-retinal barrier.

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Autores principales:	G. A. Weiner, S. H. Shah, C. M. Angelopoulos, A. B. Bartakova, R. S. Pulido, A. Murphy, E. Nudleman, R. Daneman, J. L. Goldberg
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/e38c62e273a7445fa83a47558e76aed1
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spelling	oai:doaj.org-article:e38c62e273a7445fa83a47558e76aed12021-12-02T17:01:39ZCholinergic neural activity directs retinal layer-specific angiogenesis and blood retinal barrier formation10.1038/s41467-019-10219-82041-1723https://doaj.org/article/e38c62e273a7445fa83a47558e76aed12019-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-10219-8https://doaj.org/toc/2041-1723During retinal development, waves of cholinergic neural activity play a role in retinal circuit development. Here, the authors show that this activity also contributes to layer-specific angiogenesis and formation of the blood-retinal barrier.G. A. WeinerS. H. ShahC. M. AngelopoulosA. B. BartakovaR. S. PulidoA. MurphyE. NudlemanR. DanemanJ. L. GoldbergNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q G. A. Weiner S. H. Shah C. M. Angelopoulos A. B. Bartakova R. S. Pulido A. Murphy E. Nudleman R. Daneman J. L. Goldberg Cholinergic neural activity directs retinal layer-specific angiogenesis and blood retinal barrier formation
description	During retinal development, waves of cholinergic neural activity play a role in retinal circuit development. Here, the authors show that this activity also contributes to layer-specific angiogenesis and formation of the blood-retinal barrier.
format	article
author	G. A. Weiner S. H. Shah C. M. Angelopoulos A. B. Bartakova R. S. Pulido A. Murphy E. Nudleman R. Daneman J. L. Goldberg
author_facet	G. A. Weiner S. H. Shah C. M. Angelopoulos A. B. Bartakova R. S. Pulido A. Murphy E. Nudleman R. Daneman J. L. Goldberg
author_sort	G. A. Weiner
title	Cholinergic neural activity directs retinal layer-specific angiogenesis and blood retinal barrier formation
title_short	Cholinergic neural activity directs retinal layer-specific angiogenesis and blood retinal barrier formation
title_full	Cholinergic neural activity directs retinal layer-specific angiogenesis and blood retinal barrier formation
title_fullStr	Cholinergic neural activity directs retinal layer-specific angiogenesis and blood retinal barrier formation
title_full_unstemmed	Cholinergic neural activity directs retinal layer-specific angiogenesis and blood retinal barrier formation
title_sort	cholinergic neural activity directs retinal layer-specific angiogenesis and blood retinal barrier formation
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/e38c62e273a7445fa83a47558e76aed1
work_keys_str_mv	AT gaweiner cholinergicneuralactivitydirectsretinallayerspecificangiogenesisandbloodretinalbarrierformation AT shshah cholinergicneuralactivitydirectsretinallayerspecificangiogenesisandbloodretinalbarrierformation AT cmangelopoulos cholinergicneuralactivitydirectsretinallayerspecificangiogenesisandbloodretinalbarrierformation AT abbartakova cholinergicneuralactivitydirectsretinallayerspecificangiogenesisandbloodretinalbarrierformation AT rspulido cholinergicneuralactivitydirectsretinallayerspecificangiogenesisandbloodretinalbarrierformation AT amurphy cholinergicneuralactivitydirectsretinallayerspecificangiogenesisandbloodretinalbarrierformation AT enudleman cholinergicneuralactivitydirectsretinallayerspecificangiogenesisandbloodretinalbarrierformation AT rdaneman cholinergicneuralactivitydirectsretinallayerspecificangiogenesisandbloodretinalbarrierformation AT jlgoldberg cholinergicneuralactivitydirectsretinallayerspecificangiogenesisandbloodretinalbarrierformation
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Cholinergic neural activity directs retinal layer-specific angiogenesis and blood retinal barrier formation

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