Proliferation dynamics of acute myeloid leukaemia and haematopoietic progenitors competing for bone marrow space

How leukaemia cells invade the bone marrow by outcompeting haematopoietic cells is still unclear. Here, the authors used detailed cell number measurements in conjunction with a dual pulse labelling method to determine proliferation rates and followed the in vivo dynamics of AML disease progression.

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Autores principales:	O. Akinduro, T. S. Weber, H. Ang, M. L. R. Haltalli, N. Ruivo, D. Duarte, N. M. Rashidi, E. D. Hawkins, K. R. Duffy, C. Lo Celso
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/e3963ed41c2045b095d765a722d801cc
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spelling	oai:doaj.org-article:e3963ed41c2045b095d765a722d801cc2021-12-02T16:49:32ZProliferation dynamics of acute myeloid leukaemia and haematopoietic progenitors competing for bone marrow space10.1038/s41467-017-02376-52041-1723https://doaj.org/article/e3963ed41c2045b095d765a722d801cc2018-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-02376-5https://doaj.org/toc/2041-1723How leukaemia cells invade the bone marrow by outcompeting haematopoietic cells is still unclear. Here, the authors used detailed cell number measurements in conjunction with a dual pulse labelling method to determine proliferation rates and followed the in vivo dynamics of AML disease progression.O. AkinduroT. S. WeberH. AngM. L. R. HaltalliN. RuivoD. DuarteN. M. RashidiE. D. HawkinsK. R. DuffyC. Lo CelsoNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q O. Akinduro T. S. Weber H. Ang M. L. R. Haltalli N. Ruivo D. Duarte N. M. Rashidi E. D. Hawkins K. R. Duffy C. Lo Celso Proliferation dynamics of acute myeloid leukaemia and haematopoietic progenitors competing for bone marrow space
description	How leukaemia cells invade the bone marrow by outcompeting haematopoietic cells is still unclear. Here, the authors used detailed cell number measurements in conjunction with a dual pulse labelling method to determine proliferation rates and followed the in vivo dynamics of AML disease progression.
format	article
author	O. Akinduro T. S. Weber H. Ang M. L. R. Haltalli N. Ruivo D. Duarte N. M. Rashidi E. D. Hawkins K. R. Duffy C. Lo Celso
author_facet	O. Akinduro T. S. Weber H. Ang M. L. R. Haltalli N. Ruivo D. Duarte N. M. Rashidi E. D. Hawkins K. R. Duffy C. Lo Celso
author_sort	O. Akinduro
title	Proliferation dynamics of acute myeloid leukaemia and haematopoietic progenitors competing for bone marrow space
title_short	Proliferation dynamics of acute myeloid leukaemia and haematopoietic progenitors competing for bone marrow space
title_full	Proliferation dynamics of acute myeloid leukaemia and haematopoietic progenitors competing for bone marrow space
title_fullStr	Proliferation dynamics of acute myeloid leukaemia and haematopoietic progenitors competing for bone marrow space
title_full_unstemmed	Proliferation dynamics of acute myeloid leukaemia and haematopoietic progenitors competing for bone marrow space
title_sort	proliferation dynamics of acute myeloid leukaemia and haematopoietic progenitors competing for bone marrow space
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/e3963ed41c2045b095d765a722d801cc
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Proliferation dynamics of acute myeloid leukaemia and haematopoietic progenitors competing for bone marrow space

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