Intrathymic differentiation of natural antibody-producing plasma cells in human neonates

The thymus is known as the organ of T lymphocyte development. Here authors show that terminal B cell differentiation also takes place in the thymus of human neonates, leading to antibody production against commensal and pathogenic bacteria.

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Autores principales:	Hector Cordero, Rodney G. King, Pranay Dogra, Chloe Dufeu, Sarah B. See, Alexander M. Chong, Anne-Catrin Uhlemann, Siu-Hong Ho, David M. Kalfa, Emile A. Bacha, John F. Kearney, Emmanuel Zorn
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/e3974adc67504d398d0283ef6c71a113
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spelling	oai:doaj.org-article:e3974adc67504d398d0283ef6c71a1132021-12-02T17:18:32ZIntrathymic differentiation of natural antibody-producing plasma cells in human neonates10.1038/s41467-021-26069-22041-1723https://doaj.org/article/e3974adc67504d398d0283ef6c71a1132021-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-26069-2https://doaj.org/toc/2041-1723The thymus is known as the organ of T lymphocyte development. Here authors show that terminal B cell differentiation also takes place in the thymus of human neonates, leading to antibody production against commensal and pathogenic bacteria.Hector CorderoRodney G. KingPranay DograChloe DufeuSarah B. SeeAlexander M. ChongAnne-Catrin UhlemannSiu-Hong HoDavid M. KalfaEmile A. BachaJohn F. KearneyEmmanuel ZornNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Hector Cordero Rodney G. King Pranay Dogra Chloe Dufeu Sarah B. See Alexander M. Chong Anne-Catrin Uhlemann Siu-Hong Ho David M. Kalfa Emile A. Bacha John F. Kearney Emmanuel Zorn Intrathymic differentiation of natural antibody-producing plasma cells in human neonates
description	The thymus is known as the organ of T lymphocyte development. Here authors show that terminal B cell differentiation also takes place in the thymus of human neonates, leading to antibody production against commensal and pathogenic bacteria.
format	article
author	Hector Cordero Rodney G. King Pranay Dogra Chloe Dufeu Sarah B. See Alexander M. Chong Anne-Catrin Uhlemann Siu-Hong Ho David M. Kalfa Emile A. Bacha John F. Kearney Emmanuel Zorn
author_facet	Hector Cordero Rodney G. King Pranay Dogra Chloe Dufeu Sarah B. See Alexander M. Chong Anne-Catrin Uhlemann Siu-Hong Ho David M. Kalfa Emile A. Bacha John F. Kearney Emmanuel Zorn
author_sort	Hector Cordero
title	Intrathymic differentiation of natural antibody-producing plasma cells in human neonates
title_short	Intrathymic differentiation of natural antibody-producing plasma cells in human neonates
title_full	Intrathymic differentiation of natural antibody-producing plasma cells in human neonates
title_fullStr	Intrathymic differentiation of natural antibody-producing plasma cells in human neonates
title_full_unstemmed	Intrathymic differentiation of natural antibody-producing plasma cells in human neonates
title_sort	intrathymic differentiation of natural antibody-producing plasma cells in human neonates
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/e3974adc67504d398d0283ef6c71a113
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Intrathymic differentiation of natural antibody-producing plasma cells in human neonates

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